More complications in uncemented compared to cemented hemiarthroplasty for displaced femoral neck fractures: a randomized controlled trial of 201 patients, with one year follow-up

Moerman, Sophie; Mathijssen, Nina M C; Niesten, Dieu Donne; Riedijk, Roeland; Rijnberg, W. J.; Koëter, Sander; Hei, Keetie Kremers van de; Tuinebreijer, W.E.; Molenaar, Tim L.; Nelissen, Rob G H H; Vochteloo, Anne J. H.

doi:10.1186/s12891-017-1526-0

Cited by 66 publications

(61 citation statements)

References 33 publications

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“…After duplication and reading full-text, sixteen studies were enrolled in this review. Among the sixteen studies, twelve of them were RCT [13,14,[18][19][20][21][22][23][24][25][26][27] and four of them were prospective cohort studies [3,[28][29][30]. There were 2180 hips analyzed in the 16 studies:…”

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

“…There was a low risk bias for the RCTs included. Eight studies had adequate random sequence regeneration: two computer regeneration [13,18] and six envelope regeneration [14,[20][21][22][23]27]. Eight studies mentioned allocation concealment [13,14,18,[20][21][22][23]27].…”

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

“…Eight studies had adequate random sequence regeneration: two computer regeneration [13,18] and six envelope regeneration [14,[20][21][22][23]27]. Eight studies mentioned allocation concealment [13,14,18,[20][21][22][23]27]. Of the sixteen studies, eight studies used observed blinding [13,14,18,19,22,23,26,27], ten studies reported complete outcome [13, 14, 18-23, 25, 27], and ten studies reported all outcome date without reporting bias [13, 14, 18-23, 25, 27].…”

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

“…Eight studies mentioned allocation concealment [13,14,18,[20][21][22][23]27]. Of the sixteen studies, eight studies used observed blinding [13,14,18,19,22,23,26,27], ten studies reported complete outcome [13, 14, 18-23, 25, 27], and ten studies reported all outcome date without reporting bias [13, 14, 18-23, 25, 27]. For prospective cohorts, three studies received eight score points [3,28,30] and one study received seven score points [29].…”

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

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Cemented versus uncemented arthroplasty for the management of femoral neck fractures in the elderly

Yang

Jiang

et al. 2020

Preprint

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Background Hemiarthroplasty and total hip arthroplasty (TKA) are commonly used to treat unstable femoral neck fractures in older patients. However, there is no consensus on the use of cement during hemiarthroplasty and TKA. Previous reviews on this subject included small number of studies and lacked evidence grading of outcomes. In this study, we aimed to compare the outcomes of cemented and uncemented arthroplasty for the treatment of femoral neck fractures in older patients. Methods A meta-analysis was conducted according to the guidelines of the Cochrane Collaboration using online databases (Pubmed, Cochrane Central Register of Controlled Trials, and Ovid). The quality of the included studies was assessed using the Cochrane Collaboration tool and Newcastle-Ottawa Scale. Prospective cohort studies and randomized controlled trials (RCT) of cemented arthroplasty versus uncemented arthroplasty for treatment of femoral neck fractures were analyzed using Review Manager (version 5.2) software. Results Sixteen studies were included in the meta-analysis. Cemented arthroplasty was found to be superior to uncemented arthroplasty with respect to reoperation rate, complications related to prosthesis, residual pain, and operation time. There were no significant between-group differences with respect to local and general complications, duration of hospital stay, hip function, and mortality. Conclusion Compared with cemented arthroplasty, uncemented arthroplasty was associated with a greater risk of complications related to prosthesis, reoperation rate, residual pain, and longer operation time. However, the results of this meta-analysis should be interpreted cautiously owing to some limitations. Further studies are required to provide more robust evidence.

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Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

Section: Characteristics and Qualities Of The Studies Includedmentioning

confidence: 99%

See 2 more Smart Citations

Cemented versus uncemented arthroplasty for the management of femoral neck fractures in the elderly

Yang

Jiang

et al. 2020

Preprint

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“…After automatic duplicate removal, 639 articles were saved and 24 studies were identi ed [17][18][19][20][21][22][23][24][25][26][27][28]16,29,15,[30][31][32][33][34][35][36][37][38] (Fig 1. PRISMA study ow diagram).…”

Section: Identi Cation Of Studiesmentioning

confidence: 99%

Comparison Between Cemented and Uncemented Hemiarthroplasty in Patients With Femoral Neck Fractures: A Systematic Review and Meta-analysis

Tang¹,

Liu²,

Chen³

et al. 2020

Preprint

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BackgroundWe performed an updated systematic review and meta-analysis to compare the outcomes of CHA and UCHA in patients with FNFs.MethodsWe searched 6 English databases (Cochrane Library, ScienceDirect, PubMed, Embase, Medline, and Web of Science) and 4 Chinese databases (CNKI, VIP, Wang Fang, and Sino Med) in July 2020. The quality of each study was assessed according to the Cochrane handbook of systematic reviews. Data were pooled as risk ratios (RRs) and weighted mean differences (WMDs) with 95% confidence intervals (95% CIs). We used the random-effects model despite the heterogeneity among the studies. Data regarding baseline characteristics, hip function, complications both prosthetic-related and common, and operative outcomes are reported. ResultsA total of 24 RCTs based on 22 trials involving 3119 patients (CHA, 1575; UCHA, 1544) were included. Patients in CHA group show better hip function with HHS within 6 weeks (WMD=9.097, 95% CI, 3.034-15.161; P<0.003), 3 months (WMD=3.347, 95% CI, 1.478-5.216; P<0.001), 12 months (WMD=2.183, 95% CI, 0.161-4.205; P=0.034). The pooled results show that CHA had lower rates of refracture (RR=0.227, 95% CI, 0.135-0.381; P<0.0001), subsidence or loosening (RR=0.295, 95% CI, 0.112,0.778; P<0.014) and revision (RR=0.468, 95% CI, 0.279-0.786; P=0.004). Furthermore, CHA group tend to have lower pain(VAS score) (WMD=-0.568, 95% CI, -0.897 to -0.239; P=0.001), lower rate of pressure injury(RR=0.432, 95% CI, 0.221-0.846; P=0.014) and mortality at 1 year after surgery(RR=0.852, 95% CI, 0.727-0.998; P=0.047). UCHA showed a shorter operative duration(WMD=8.739, 95% CI, 6.354-11.124; P<0.0001).ConclusionsThis meta-analysis demonstrates that CHA has better hip function, lower rates of refracture, subsidence or loosening, revision, pressure ulcer, pain and one-year mortality than UCHA, while UCHA has shorter operative duration.

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Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis

Lewis

Macey

Stokes

et al. 2022

Cochrane Database of Systematic Reviews

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BackgroundHip fractures are a major healthcare problem, presenting a major challenge and burden to patients and healthcare systems. The number of hip fractures globally is rising rapidly. The majority of intracapsular hip fractures are treated surgically. ObjectivesTo assess the relative effects (benefits and harms) of all surgical treatments used in the management of intracapsular hip fractures in older adults, using a network meta-analysis of randomised trials, and to generate a hierarchy of interventions according to their outcomes. Search methodsWe searched CENTRAL, MEDLINE, Embase, Web of Science, and five other databases in July 2020. We also searched clinical trials databases, conference proceedings, reference lists of retrieved articles and conducted backward-citation searches. Selection criteriaWe included randomised controlled trials (RCTs) and quasi-RCTs comparing different treatments for fragility intracapsular hip fractures in older adults. We included total hip arthoplasties (THAs), hemiarthroplasties (HAs), internal fixation, and non-operative treatments. We excluded studies of patients with specific pathologies other than osteoporosis or resulting from high energy trauma. Data collection and analysisTwo review authors independently assessed studies for inclusion. One review author completed data extraction which was checked by a second. We collected data for three outcomes at different time points: mortality and health-related quality of life (HRQoL) -both reported within 4 months, at 12 months, and after 24 months of surgery, and unplanned return to theatre (at end of study follow-up).We performed a network meta-analysis (NMA) with STATA software, using frequentist methods, and calculated the differences between treatments using risk ratios (RRs) and standardised mean differences (SMDs) and their corresponding 95% confidence intervals (CIs). We also performed direct comparisons using the same codes. Main resultsWe included 119 studies (102 RCTS, 17 quasi-RCTs) with 17,653 participants with 17669 intracapsular fractures in the review; 83% fractures were displaced. The mean participant age ranged from 60 to 87 years and 73% were women.

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More complications in uncemented compared to cemented hemiarthroplasty for displaced femoral neck fractures: a randomized controlled trial of 201 patients, with one year follow-up

Cited by 66 publications

References 33 publications

Cemented versus uncemented arthroplasty for the management of femoral neck fractures in the elderly

Cemented versus uncemented arthroplasty for the management of femoral neck fractures in the elderly

Comparison Between Cemented and Uncemented Hemiarthroplasty in Patients With Femoral Neck Fractures: A Systematic Review and Meta-analysis

Surgical interventions for treating intracapsular hip fractures in older adults: a network meta-analysis

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