In recent years, machine learning methods has been widely used in various fields, such as finance, spatial sciences, smart grid, intelligent transportation, renewable energy, agriculture, especially medicine. In the era of big medical data, the advantage of machine learning is that it can predict and diagnose through the analysis of a large number of clinical data, and its performance is very close and competitive to or even better than the performance of clinicians. This paper focuses on the application of machine learning techniques in the field of stomatology and detailedly describes application cases involving oral cancer, dental caries, periodontitis, dental pulp diseases, periapical lesions, oral implants, and orthodontics. Finally, the research obstacles and future work are discussed.