Morphological features of experimental chronic tonsillitis

Abstract

Purpose. To study the morphological features of the palatine tonsils of experimental animals in normal conditions and during the modeling of chronic tonsillitis. Material and methods. A model of experimental chronic tonsillitis was created on 15 rabbits, 5 animals were included in the control group. Chronic tonsillitis was simulated under general anesthesia. Staphylococcus aureus was injected into the palatine tonsils of animals in a dose of 3 million microbial bodies. Morphological studies of the tissues of the palatine tonsils of animals in the control group and the experimental group were carried out one month after modeling. Results. The results of a morphological study of the tonsils of the experimental group of rabbits clearly demonstrated manifestations of chronic tonsillitis (proliferation of connective tissue in the subepithelial layer, weakening of the muscle tone of the vessels with a simultaneous change in the permeability of the vascular wall, developing hyalinosis). Conclusion. Morphological studies of the tonsils have confirmed the similarity of the modeled chronic pathology with the disease of a similar human organ. Key words: palatine tonsils, rabbits, chronic tonsillitis model, morphological studies.