Morphology control of hydroxyapatite through hydrothermal process

Syntheses of Single-Crystal Apatite Particles with Preferred Orientation to the <i>a</i>- and <i>c</i>-Axes as Models of Hard Tissue and Their Applications

“…Numerous studies on orientation-controlled HAp particles, coating layers, and dense ceramics have been reported. c-Axis-oriented fiberlike and a(b)-axis-oriented plate-like HAp particles can be synthesized using the homogeneous precipitation method, [30][31][32][33] hydrothermal method, [34][35][36] and electrochemical method. 37,38) This review first describes the syntheses process of singlecrystal apatite particles with preferred orientation to the a(b)-and c-axes as models for tooth enamel and bones, respectively, together with characterization of the resulting apatite particles.…”

Microstructure of hydroxyapatite- and octacalcium phosphate-coatings formed on magnesium by a hydrothermal treatment at various pH values

“…On the other hand, the crystal shape, size and crystallographic orientation of synthesized HAp particles or flakes have been well investigated [23][24][25][26][27][28][29][30]. It was revealed that these factors affect cytokine production [31,32], the proliferation of tumor cells [33] and luminescence properties [25].…”

Design of experiments (DOE) for the optimization of hydrothermal synthesis of hydroxyapatite nanoparticles

“…[18][19][20][21][26][27][28][29] It is known that HAp nanorods can be synthesized; however, the preparation of nano-sized particles with high aspect ratio, appropriate stoichiometry and high crystallinity still remains an important task. 4,5,[19][20][21][25][26][27][28][29][30][31][32] The hydrothermal method, which works at high temperature and high pressure, is the most frequently used technique for one-dimensional growth of HAp. This method enables the synthesis of HAp powders with high degree of crystallinity which are relatively stable in physiological medium.…”

“…For instance, some works show that the rod-like HAp is synthesized in acidic 5,35 or approximately neutral conditions, 28 and others show that these nanorods are synthesized under alkaline conditions. [30][31][32]36 Moreover, only few experimental parameters were evaluated in each study.…”