Mortality in systolic heart failure revisited: Ischemic versus non-ischemic cardiomyopathy

Gajanana, Deepakraj; Shah, Mahek; Junpapart, Parichart; Romero‐Corral, Abel; Figueredo, Vincent M.; Bozorgnia, Behnam

doi:10.1016/j.ijcard.2016.08.316

Cited by 24 publications

(24 citation statements)

References 16 publications

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“…On the one hand, as a result of the strict inclusion criteria the patients in our study had a smaller LV dimension, specifically LVESV; on the other hand, all patients in our study were diagnosed with dilated nonischemic cardiomyopathy, which has been proven to be associated with better prognosis in heart failure compared with ischemic cardiomyopathy with or without CRT. [19][20][21] Last but not the least, the results of our study supported the safety of short-term (≤ 3 months) cessation of pacing for CRT superresponders, for instance, in scenarios when pocket infection occurs and the generator needs to be retracted and sterilized.…”

Section: Discussionsupporting

confidence: 74%

“…It is worth mentioning that our study showed only decrease in LVEF after 6 months without pacing; in contrast, all clinical and echocardiographic parameters deteriorated after the same time course in the report by Cay et al The difference in disease progression between the studies could probably be attributed to the difference in characteristics of recruited participants. On the one hand, as a result of the strict inclusion criteria the patients in our study had a smaller LV dimension, specifically LVESV; on the other hand, all patients in our study were diagnosed with dilated nonischemic cardiomyopathy, which has been proven to be associated with better prognosis in heart failure compared with ischemic cardiomyopathy with or without CRT …”

Section: Discussionmentioning

confidence: 99%

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Cessation of pacing in super‐responders of cardiac resynchronization therapy: A randomized controlled trial

Liang

Wang

Zhang

et al. 2018

Cardiovasc electrophysiol

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Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Cessation of pacing in super‐responders of cardiac resynchronization therapy: A randomized controlled trial

Liang

Wang

Zhang

et al. 2018

Cardiovasc electrophysiol

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“…Some studies show similar prognosis in such patients24 while a US-based study showed that ICMP has a worse prognosis 25. A recent randomised trial of patients with NICMP comparing ICD therapy to no ICD showed greater than 90% survival at 2 years in both groups 22.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of non-acute ischaemic cardiomyopathy in a Pakistani cohort

et al. 2019

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Heart failure with reduced left ventricular ejection fraction (HFrEF) is a frequently encountered clinical scenario. Coronary angiography (CAG) is usually performed to assess obstructive epicardial coronary artery disease (CAD) and the resultant ischaemia as causes of HFrEF.ObjectivesTo determine the frequency of obstructive CAD (OCAD) in patients with HFrEF and its independent predictors and outcomes.MethodsRetrospective observational study in Tabba Heart Institute on patients who underwent CAG during the past 4 years. Patients with prior known CAD or revascularisation were excluded. OCAD was defined as per the criteria from Felker et al. Regression modelling was performed to evaluate the predictors of OCAD. Survival was compared between the groups using the log rank test.ResultsOut of 2235 patients who underwent CAG, 260 had HFrEF as a primary indication for CAG and, of these, 119 (45.8%) had OCAD. Major predictors of OCAD were age >50 years at presentation (OR 2.0, 95% CI 1.1 to 3.7), presence of chest pain (OR 4.3, 95% CI 2.3 to 8.1), family history of premature CAD (OR 2.8, 95% CI 1.3 to 5.9) and utilisation of non-invasive (NIV) stress testing before CAG (OR 3.6, 95% CI 1.8 to 7.1). Survival was significantly lower (log rank p<0.001) in patients with OCAD with no revascularisation compared with OCAD with revascularisation or those who had non-obstructive CAD, and the latter two groups had comparable survival.ConclusionsOCAD is detected in nearly half of the patients with reduced left ventricular systolic function undergoing CAG. Clinical judgement based on thorough history and use of NIV stress testing can help in appropriate patient selection for this test.

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“…Prevalence of coronary artery disease in Indonesia has increased from 0.5% in 2013 to 1.5% in 2018 [ 2 ]. Ischemic cardiomyopathy has a worse prognosis than non-ischemic cardiomyopathy, with a 5-year survival rate at as high as 50% while non-ischemic cardiomyopathy is 33% [ 3 ]. The most common cause of death in ischemic cardiomyopathy is progressivity of heart failure and sudden cardiac death [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Correlation Between T Peak to End Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patients

et al. 2020

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Background: Ischemic cardiomyopathy is the most frequent etiology of heart failure with reduced ejection fraction (HFrEF) and a result of ventricular structural, functional and electrical remodeling. T peak to end (Tpe) interval is an electrocardiographic parameter that represents repolarization heterogeneity and had prognostic value for ventricular arrhythmia. Patients with ischemic cardiomyopathy face a significant burden of arrhythmias. Mechanical dispersion is a functional remodeling parameter that can be measured by time to peak longitudinal strain using speckle tracking echocardiography. This study aimed to assess the relationship between Tpe interval with time to peak longitudinal strain in ischemic cardiomyopathy patients. Methods: This study was conducted with an observational analytical cross-sectional design. Ischemic cardiomyopathy subjects were included at Dr. Hasan Sadikin General Hospital, Bandung, from August to October 2019. Tpe interval was measured manually with the tangential method. Time to peak longitudinal strain was measured using speckle tracking echocardiography. The correlation between Tpe interval and time to peak longitudinal strain was analyzed using Pearson correlation. Results: A total of 30 subjects were included in this study. The average age was 58 ± 8 years old, and the average left ventricular ejection fraction was 27±5.5%. The average of Tpe interval was 83.4 ± 7.62 ms, and the average time to peak longitudinal strain was 93.13 ± 34.51 ms. The Pearson correlation test showed a significant weak positive correlation (r = 0.386, 95% confidence interval: 0.029-0.743, P = 0.018) between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients. Conlucions: There was a significant weak positive correlation between Tpe interval and time to peak longitudinal strain in ischemic cardiomyopathy patients.

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Mortality in systolic heart failure revisited: Ischemic versus non-ischemic cardiomyopathy

Cited by 24 publications

References 16 publications

Cessation of pacing in super‐responders of cardiac resynchronization therapy: A randomized controlled trial

Cessation of pacing in super‐responders of cardiac resynchronization therapy: A randomized controlled trial

Prevalence of non-acute ischaemic cardiomyopathy in a Pakistani cohort

Correlation Between T Peak to End Interval and Left Ventricular Time to Peak Longitudinal Strain in Ischemic Cardiomyopathy Patients

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