MoS₂ Nanosheets–Cyanobacteria Interaction: Reprogrammed Carbon and Nitrogen Metabolism

Abstract

Fully understanding the environmental implications of engineered nanomaterials is crucial for their safe and sustainable use. Cyanobacteria, as the pioneers of the planet earth, play important roles in global carbon and nitrogen cycling. Here, we evaluated the biological effects of molybdenum disulfide (MoS2) nanosheets on a N2-fixation cyanobacteria (Nostoc sphaeroides) by monitoring growth and metabolome changes. MoS2 nanosheets did not exert overt toxicity to Nostoc at the tested doses (0.1 and 1 mg/L). On the contrary, the intrinsic enzyme-like activities and semiconducting properties of MoS2 nanosheets promoted the metabolic processes of Nostoc, including enhancing CO2-fixation-related Calvin cycle metabolic pathway. Meanwhile, MoS2 boosted the production of a range of biochemicals, including sugars, fatty acids, amino acids, and other valuable end products. The altered carbon metabolism subsequently drove proportional changes in nitrogen metabolism in Nostoc. These intracellular metabolic changes could potentially alter global C and N cycles. The findings of this study shed light on the nature and underlying mechanisms of bio-nanoparticle interactions, and offer the prospect of utilization bio-nanomaterials for efficient CO2 sequestration and sustainable biochemical production.

Two‐Dimensional Transition Metal Dichalcogenides Trigger Trained Immunity in Human Macrophages through Epigenetic and Metabolic Pathways

“…Indeed, previous work implied that MoS 2 possesses radical scavenging activities, [ 51 ] and a recent study published during the preparation of the present manuscript confirmed some but not all of these enzyme‐mimetic properties. [ 52 ] At any rate, we may conclude that while MoS 2 nano‐sheets are non‐toxic, they are not inert.…”

Therapeutic Delivery of Nanoscale Sulfur to Suppress Disease in Tomatoes: In Vitro Imaging and Orthogonal Mechanistic Investigation

“…The features with a VIP >0.1 are regarded as responsible for separation. 59 Rhizosphere Bacteria Characterization. Rhizosphere soils were defined as the soil tightly adhering to the root tissues.…”

“…The impact value threshold >0.1 was considered as significantly affected. The features with a VIP >0.1 are regarded as responsible for separation …”

Lighting Up Agricultural Sustainability in the New Era through Nanozymology: An Overview of Classifications and Their Agricultural Applications

“…The combination of nanozymes with other agricultural technologies is expected to be an innovative and powerful way to improve agricultural sustainability. For example, nanozymes can enhance agricultural microorganisms by their nanoproperties, such as enhanced metabolic processes of Nostoc in cyanobacteria due to MoS 2 nanozymes, 103 which is expected to indirectly promote crop yields. Moreover, some nanozymes with a definite framework structure, such as MOFs, are expected to play the role of nanocarriers of agrochemicals to attain the goal of intelligently controllable release of agrochemicals, 104 in addition to their catalytic activity in agricultural practice.…”