Mössbauer Spectroscopy In Biological and Biomedical Research

The Mössbauer effect using 57Fe-ferrabisdicarbollide ([o-57FESAN]−): a glance into the potential of a low-dose approach for glioblastoma radiotherapy

“…In fact, in biological systems, iron is by far one of the most structurally and relevant metal ions and 57 Fe Mössbauer spectroscopy has been very useful in the elucidation of the electronic structures of iron-containing biomolecules, the role of iron in living processes and pathological changes in living systems, organs and tissues. 3–6…”

“…In fact, in biological systems, iron is by far one of the most structurally and relevant metal ions and 57 Fe Mössbauer spectroscopy has been very useful in the elucidation of the electronic structures of iron-containing biomolecules, the role of iron in living processes and pathological changes in living systems, organs and tissues. [3][4][5][6] Radiation therapy (RT) is the most frequently used therapeutic option for the treatment of cancer but high doses of ionizing radiation are delivered to tumours since only a small fraction of the absorbed dose can damage cancer cells. Moreover, the efficacy of RT is limited by the resistance of tumours as well as by the toxicity to normal cells and tissues.…”

Structural and magnetic study of the iron cores in iron(III)-polymaltose pharmaceutical ferritin analogue Ferrifol®

“…Various structural investigations of ferritin iron cores by transmission electron microscopy (TEM), X-ray absorption spectroscopy and electron nanodiffraction resulted in a variety of iron core models [12][13][14][15][16][17][18][19]. Applications of magnetization and Mössbauer spectroscopy measurements in the study of various ferritins and its pharmaceutical analogues demonstrated spread approaches also (see, for example, [20][21][22][23][24][25][26][27][28][29], for review see [30][31][32]).…”

Evaluation of the Debye temperature for iron cores in human liver ferritin and its pharmaceutical analogue, Ferrum Lek, using Mössbauer spectroscopy

“…Comparative studies of ferritin and its analogues were done using various techniques such as extended X-ray absorption fine structure [7][8][9], electron diffraction [10], magnetization measurements [11][12][13][14][15][16] and Mössbauer spectroscopy (for reviews see [16,17] and see, for instance, also [9,[18][19][20][21][22][23][24][25][26][27][28]). These studies demonstrated some similarities and differences of physical parameters for ferritin and its analogues.…”