2021
DOI: 10.1101/2021.10.25.465774
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Mouse lemur, a new animal model to investigate cardiac pacemaker activity in primates

Abstract: Mouse lemur (Microcebus murinus) is one of the smallest and more ancestral primates known so far. It is an emerging model of senescence and neurodegeneration, thanks to its genetic proximity to humans compared to rodents. Thus, M. murinus could help to better understand cardiac physiology in humans. Nevertheless, the cardiac physiology of M. murinus is still unknown. We had the opportunity to characterize cardiac activity in mouse lemurs, focusing on the pacemaker activity generation by the Sinoatrial node (SA… Show more

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