Movement disorder emergencies

Frucht, Steven J.

doi:10.1007/s11910-005-0073-5

Cited by 9 publications

(4 citation statements)

References 123 publications

(108 reference statements)

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“…Several factors, such as stress, infection and certain drugs, are risk factors for tics exacerbation (30). Tics status is a serious and dangerous condition characterized by ongoing tics that cannot be willfully controlled for more than few seconds and tics that display a real risk to the persons health, as well as those that compromise normal functioning in public, in a classroom or at work (32). When diagnosing tics, every clinician should identify if there were any provoking factors and eliminate them.…”

Section: Ticsmentioning

confidence: 99%

“…Every clinician must keep in mind that patients affected by this condition may be resistant to drugs like anticholinergics, baclofen, benzodiazepines, dopamine blockers, or dopamine depleters. Therefore, in many cases sedation and paralysis may be the right choice of treatment (32). The other very effective treatment of status dystonicus is DBS (36).…”

Section: Dystoniamentioning

confidence: 99%

“…This condition relates to the usage of neuroleptics. Intravenous diphenhydramine has been documented to be effective in treating this emergency (31,32).…”

Section: Dystoniamentioning

confidence: 99%

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Emergencies in movement disorders

Hero¹,

Rački²,

Vuletić³

2021

Rad Hrvatske akademije znanosti i umjetnosti

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Movement disorders constitute a large group of diseases that affect the control of voluntary motor activity without a direct impact on sensation and strength. Usual clinical course is slow, progressive and can be treated in an outpatient clinic. However, there are several emergencies regarding movement disorders that are serious medical conditions and may result in death if not recognized and treated promptly. Every neurologist should be aware of these states because they can develop during the course of a patient's illness. The aim of this review is to provide key features of the most common emergencies in movement disorders, including drug-induced emergencies, emergencies in Parkinson's disease, chorea and ballismus, tics, myoclonus and dystonia.

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Section: Ticsmentioning

confidence: 99%

Section: Dystoniamentioning

confidence: 99%

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Emergencies in movement disorders

Hero¹,

Rački²,

Vuletić³

2021

Rad Hrvatske akademije znanosti i umjetnosti

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“…A potentially painful situation can be present [52,56]. Even though rare, the involvement of laryngeal or respiratory muscles can occur in TDk [58] and TDt [59] and can be very distressing or even life-threatening.…”

Section: Dystonia -Different Prospectsmentioning

confidence: 99%

Tardive Dystonia due to D2 Antagonists and Other Agents

Σκώκου¹,

Tsermpini²,

Giamarelou³

et al. 2018

Dystonia - Different Prospects

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Tardive dystonia due to D2 antagonists or other agents is a potentially severe extrapyramidal side effect emerging after long-term drug treatment, prevalent but not limited to psychiatric populations. Its course is often deteriorating, and available treatments are frequently far from satisfying. It presents with sustained muscle contractions, abnormal postures, and repetitive twisting movements and leads to increased psychiatric morbidity, mortality, and decline of quality of life. Inadequate clinical skill and awareness of tardive dystonia can lead to neglect or misdiagnoses, considered as conversion symptoms or of psychogenic origin. Since the syndrome is persistent and often treatment resistant, prevention should be a mainstay of clinical care. Emerging evidence supports positive effects of atypical antipsychotics, particularly quetiapine and clozapine. Therapies such as tetrabenazine, valbenazine, deutetrabenazine, anticholinergics, baclofen, benzodiazepines, vitamin E, or non-pharmacologic interventions, namely botulinum toxin A, deep-brain stimulation, have been found to be helpful in some cases of tardive dystonia. This chapter comprehensively illustrates multiple aspects of this entity, including recent advances on etiology, pathophysiology, clinical presentation, epidemiology, pharmacogenomics, and treatment, aiming to enhance and deepen clinicians' and researchers' awareness of tardive dystonia, with the final goal of ameliorating patients' prognosis and quality of life.

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