Mp09-14 en-Bloc Enucleation Technique Using Moses Laser (En-Bloc Molep) vs en-Bloc Holep: Comparing Intra and Post-Operative Outcomes for en-Bloc Enucleation Technique With Early Apical Release, to Treat Patients Affected by Benign Prostatic Enlargement (Bpe)

Socarrás, M.E. Rodríguez; Álamo, J. Fernández Del; Esposito, Fabio; Elbers, Javier Reinoso; Rivas, Juan Gómez; Carrión, D.M.; Rivera, Vanesa Cuadros; González, Luis Llanes; Dago, Pablo Juarez del; Sancha, Fernando Gómez

doi:10.1097/ju.0000000000001954.14

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“…OT was reported in six studies 4,6–8,14,15 (277 MoLEP vs. 336 HoLEP). Study heterogeneity was relatively pronounced ( I 2 = 73.3%, p = 0.002), and a random‐effects model was used to analyze the data, which showed that the MoLEP group had a significantly shorter mean OT than the HoLEP group, with a statistically significant difference (WMD = −15.02 min, 95% CI [−20.50, − 9.53], p < 0.001) (Figure 4).…”

Section: Resultsmentioning

confidence: 99%

“…After a full‐text reading of the remaining 46 articles, 34 that did not meet the inclusion criteria were excluded. Twelve studies were finally included in this meta‐analysis 4–8,10,14–19 . The literature search flow and results are shown in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

“…Four studies 8,14,15,17 (214 MoLEP vs. 267 HoLEP) reported the HT. As no significant heterogeneity was found among the studies ( I 2 = 61.9%, p = 0.049), a random‐effects model was used to combine the data.…”

Section: Resultsmentioning

confidence: 99%

“…ET was reported in seven studies 5,8,10,14–17 (335 MoLEP vs. 400 HoLEP). The heterogeneity of the studies was significant ( I 2 = 76.3%, p = 0.000), and a random‐effects model was used to analyze the data.…”

Section: Resultsmentioning

confidence: 99%

“…This meta‐analysis included 12 studies 4–8,10,14–19 and 1160 participants (514 MoLEP vs. 646 HoLEP). Meta‐analysis results showed that, in terms of safety indicators, compared with HoLEP, MoLEP had statistically significant differences in OT, ET, HT, IBL, and LOS ( p < 0.05) and no significant difference in CT and MPC ( p > 0.05).…”

Section: Discussionmentioning

confidence: 99%

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Efficiency and clinical outcomes of Moses technology for holmium laser enucleation of the prostate: An evidence‐based analysis

Meng

et al. 2022

The Prostate

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Background To compare the safety and clinical efficacy of Moses laser enucleation of the prostate (MoLEP) with those of holmium laser enucleation of the prostate (HoLEP) for treating benign prostatic hyperplasia (BPH). Methods We systematically searched PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang databases, and SinoMed databases. The retrieval period was from the establishment of the database to March 2022. Stata17.0 was used for calculations and statistical analyses. Results This study included 12 articles comprising 1160 patients for meta‐analysis. Compared with those of the HoLEP group, the hemostasis time (weighted mean difference [WMD] = −4.66, 95% confidence interval [CI] [−6.47, −2.84], p < 0.001), enucleation time (WMD = −7.23, 95% CI [−10.67, −3.79], p < 0.001), operative time (WMD = −15.02, 95% CI [−20.50, −9.53], p< 0.001), length of hospital stay (WMD = −15.02, 95% CI [−20.50, −9.53], p< 0.001), intraoperative blood loss (WMD = −11.19, 95% CI [−12.94, −9.44], p< 0.001), and total postoperative complications rate (OR = 0.51, 95% CI [0.32, 0.81], p = 0.004) were shorter in the MoLEP group. Postoperative quality of life (WMD = 0.30, 95% CI [0.00, 0.59], p = 0.047) was lower in the HoLEP group, and there were no statistically significant differences in the International Prostate Symptom Score, postoperative maximum urinary flow rate, and postoperative residual urine (p > 0.05). Conclusion MoLEP has more advantages than HoLEP in terms of safety, shorter operation time and hospital stay, and fewer complications. However, this conclusion needs to be verified with a larger sample size, longer follow‐up time, and multicenter randomized controlled trial data.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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