Mp72-11 Depression and Catastrophizing Predicts Suicidal Ideation in Tertiary Care Patients With Interstitial Cystitis/Bladder Pain Syndrome (Ic/Bps)

Abstract

after bladder hydrodistension, are reportedly not the specific observation of IC/BPS. We therefore investigated whether the narrow-band imaging (NBI) system, which can evaluate superficial vascular structures, is useful to identify mucosal lesions without bladder distension, for the diagnosis of non-Hunner IC/BPS. METHODS: Under local anesthesia, cystoscopic examination with NBI was performed in 1,298 IC/BPS cases. After baseline evaluation of the entire bladder mucosa, patients were divided to those with Hunner or non Hunner IC.RESULTS: Among 1,298 cases, 1,279 patients (98.7%) showed the hypervascular, overstretched bladder mucosa before bladder distension by NBI, in contrast to the folded whitish mucosa with few vessels of the normal bladder (Fig. 1). In those 1279 cases, Hunner lesions were found in 727 cases (57%), atypical Hunner lesions showing hypervascular, edematous mucosal changes in 51 cases (3%) and non-Hunner lesions characterized by spotty superficial neovascular lesions identified without bladder distension (Fig. 2) in 480 cases (33%).CONCLUSIONS: NBI is useful for detecting Hunner and non-Hunner lesions in 93% of patients. The hypervascular, overstretched condition of the bladder mucosa found in the majority of patients and non-Hunner lesions in one third of patients may indicate a hypersensitive bladder condition underlying IC/BPS symptoms.