Background: Proper and quick diagnosis of the musculoskeletal abnormalities is important to avoid any future defect. Objectives: To estimate the accomplishment of sonographic investigation in evaluating several kinds of wrist joint disorders. Methods: This prospective study was achieved at Khartoum state hospitals for a period of 2 years; on 175 participants 100 males and 75 females their age ranging from 18 to 63 who came to ultrasound department had wrist joint pain. Medical history and informed consent were taken. Results: Spectrum of wrist joint disorders found out by ultrasound, ganglion cysts 18.29% (32 of 175), joint effusion 14.29% (25 of 175), triangular fibrocartilage complex tear 13.14% (23 of 175), carpal tunnel syndrome 12 % ( 21 of 175), arthritis 10.86 % (19 of 175), scapholunate tear 8.57 % (15 of 175), tenosynovitis 8% ( 14 of 175), avascular necrosis 8% (14 of 175),tendon tear 4% (7 of 175) and Neoplasm 2.86% (5 of 175). Conclusion: Ultrasound become widespread method in assessment of musculoskeletal system. It became a first-line in diagnostic purposes. Its perfect features make it trustable and safety modality to evaluate the assortment of wrist abnormalities.