MRI of diffuse liver disease: the common and uncommon etiologies

Chundru, Surya; Kalb, Bobby; Arif-Tiwari, Hina; Sharma, Puneet; Costello, James; Martín, Diego R.

doi:10.5152/dir.2013.13148

Cited by 10 publications

(7 citation statements)

References 18 publications

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“…MRKP lüminal değişiklikleri oldukça yüksek duyarlılık ile gösterebilmesine rağmen, safra kanallarının duvarındaki değişiklikleri ortaya koymak için uygun bir sekans değildir. Bu amaç ile elde olunan intravenöz kontrast uygulanması sonrası alınan T1A gö-rüntülerde etkilenmiş olan safra kanallarında duvar kalınlaşması ve duvarda artmış kontrastlanma dikkati çeker (Resim 10a-c) [17][18][19] [12,21]. Bakır birikiminin karaciğer parankiminde BT'de dansite artışına neden olması beklenir, ancak bir yandan da yağlanmaya bağlı dansite azalması olacağından, dansite artışı tesbit edilmeyebilir.…”

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Diffüz Karaciğer Hastalıkları

Gürses¹,

Seçil²

2016

Trd Sem

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“…BT'de hipo veya hiperdens nodüller izlenebilmektedir. BT'de hiperdens olarak görülen nodüller MR'da T1A kesitlerde hiperintens, T2A kesitlerde hipointens olduğu gösterilmiştir (Resim 13) [12,21].…”

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2016

Trd Sem

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“…The diagnosis of liver diseases is based on a medical interview, physical examination, blood examination, imaging and biopsy findings. Magnetic resonance imaging (MRI) has been reported to be an appropriate modality for detecting hepatic fat and iron deposition in patients with diffuse liver diseases (2). Fatty liver can be diagnosed using the gradient-echo (GRE) technique, by the difference in signal intensity between in-phase and opposed-phase images of the liver parenchyma.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of Magnetic Resonance Imaging for the Diagnosis of Hemochromatosis with Severe Hepatic Steatosis in Nonalcoholic Fatty Liver Disease

et al. 2016

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The ratio of the number of patients with non-alcoholic steatohepatitis (NASH) to the total number of patients with liver dysfunction has increased in many countries around the world. Liver dysfunction is also caused by multiple blood transfusions in patients with leukemia and other hematological diseases, with liver dysfunction often accompanied by secondary hemochromatosis. This study describes a 25-year-old man with secondary hemochromatosis combined with NASH. Magnetic resonance imaging was useful for visualizing the distributions of both iron and fat in the liver of this patient in order to make a differential diagnosis and to evaluate the effect of treatment.

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“…Through this period, the nodule may develop the specific imaging features of HCC, which will obviate the need for a biopsy and provide the confirmatory diagnosis needed for pretransplant staging. Using longitudinal short-interval timecourse imaging for staging in a patient with an indeterminate nodule is therefore now believed to be more accurate and safer than biopsies (41,43).…”

Section: The Role Of Liver Biopsymentioning

confidence: 99%

MRI of hepatocellular carcinoma: an update of current practices

Arif-Tiwari

Kalb

Chundru

et al. 2014

Diagn Interv Radiol

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Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and liver transplantation is the optimal treatment for selected patients with HCC and chronic liver disease (CLD). Accurate selection of patients for transplantation is essential to maximize patient outcomes and ensure optimized allocation of donor organs. Magnetic resonance imaging (MRI) is a powerful tool for the detection, characterization, and staging of HCC. In patients with CLD, the MRI findings of an arterial-enhancing mass with subsequent washout and enhancing capsule on delayed interstitial phase images are diagnostic for HCC. Major organizations with oversight for organ donor distribution, such as The Organ Procurement and Transplantation Network (OPTN), accept an imaging diagnosis of HCC, no longer requiring tissue biopsy. In patients that are awaiting transplantation, or are not candidates for liver transplantation, localized therapies such as transarterial chemoembolization and radiofrequency ablation may be offered. MRI can be used to monitor treatment response. The purpose of this review article is to describe the role of imaging methods in the diagnosis, staging, and follow-up of HCC, with particular emphasis on established and evolving MRI techniques employing nonspecific gadolinium chelates, hepatobiliary contrast agents, and diffusion weighted imaging. We also briefly review the recently developed Liver Imaging Reporting and Data System (LI-RADS) formulating a standardized terminology and reporting structure for evaluation of lesions detected in patients with CLD.H epatocellular carcinoma (HCC) is a major worldwide health concern; it is the sixth most common cancer and third leading cause of overall cancer-related mortality. HCC frequently presents as a rapidly growing tumor and has historically been associated with poor prognosis and outcomes. However, tumor screening protocols in high risk patients can lead to an earlier detection of treatable disease. Screening for HCC has resulted in significant improvements in the one-year cause-specific survival rates for new patients (1), and this is directly attributed to improved survival through the detection of early stage tumor.The five-year cumulative risk of HCC ranges from 4%-30% in patients with chronic liver disease (CLD) and cirrhosis (2-3). Multiple therapeutic strategies are available for the treatment of HCC, including medical therapy, percutaneous tumor ablation, transarterial embolic therapy, surgical resection, and liver transplantation. Of all the available methods, liver transplantation is the most effective treatment for early HCC because this method removes not only the tumor but also the entire cirrhotic liver, which is at an increased risk for developing metachronous tumors. The effectiveness of liver transplantation depends upon detecting early stage disease within specific criteria. A seminal paper by Mazzaferro et al. (4), published in 1996, established the "Milan criteria" as the most widely used guidelines for transplant eligibility. The Mila...

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MRI of diffuse liver disease: the common and uncommon etiologies

Cited by 10 publications

References 18 publications

Diffüz Karaciğer Hastalıkları

Diffüz Karaciğer Hastalıkları

Usefulness of Magnetic Resonance Imaging for the Diagnosis of Hemochromatosis with Severe Hepatic Steatosis in Nonalcoholic Fatty Liver Disease

MRI of hepatocellular carcinoma: an update of current practices

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