Mujer de 37 años con molestias abdominales y lesión focal esplénica

Inflammatory pseudotumor of spleen: a case report

“…Inflammatory pseudotumors are benign conditions of unknown etiology that may present in different locations (orbit, liver, respiratory and digestive tracts) [1,2] . Inflammatory pseudotumors of the spleen are extremely rare.…”

“…According to data released, most patients are middle – advanced age and some reports suggest a greater tendency of affection in woman [2,4] . There is no typical clinical presentation and symptoms may be disparate from abdominal pain or discomfort, fever, splenomegaly or showing signs and symptoms suggesting malignancy to incidental findings in the study of other diseases [1,4,5] .…”

“…There are different theories about its etiology: bleeding or rupture of hemangioma, bacterial infection, Epstein- Barr virus and herpes infection, inflammatory granulomatous process, vascular causes and other immune disorders. However, the real pathogenesis remains unknown [1,2,4,5,7,8] .…”

“…Preoperative biopsy of spleen is not recommended because of poor specificity, the risk of possible bleeding or tumor spread in case of malignancy, so it is recommended splenectomy and evaluation of the surgical specimen [1,2,17] .…”

“…Differential diagnoses are broad as metastasis, malignant lymphoma, inflammatory granuloma, splenic infarction, hemangiomas, hamartomas, lymphangioma, plasmacytoma, hemangioendotheliomas, angiosarcomas, reactive lymphoid hyperplasia, abscess, infectious granulomatous processes and sarcoidosis, so the final diagnosis of pseudotumor is established with the pathological anatomy study [2,4,6,12,13,15] .…”