Multi-Glycomics Platform Approach for Cancer

An, Hyun Joo; Kronewitter, Scott R.; Leoz, Lorna A. De; Peacock, Kyle S.; Lebrilla, Carlito B.

doi:10.5355/jast.2011.a129

Cited by 1 publication

(1 citation statement)

References 10 publications

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“…Glycans containing sialic acids are generally unstable under MALDI conditions as the result of the labile proton of the carboxy group. Stabilization can be achieved by derivatization such as methyl ester formation as emphasized with glycans from human serum in a study of cancer‐specific changes in glycosylation (An et al, ). The use of 2 H 3 ‐methyl‐esterification produced suitable internal standards for quantification.…”

Section: Derivativesmentioning

confidence: 99%

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2011–2012

Harvey

2015

Mass Spectrometry Reviews

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This review is the seventh update of the original article published in 1999 on the application of MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2012. General aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, and fragmentation are covered in the first part of the review and applications to various structural types constitute the remainder. The main groups of compound are oligo- and poly-saccharides, glycoproteins, glycolipids, glycosides, and biopharmaceuticals. Much of this material is presented in tabular form. Also discussed are medical and industrial applications of the technique, studies of enzyme reactions, and applications to chemical synthesis. © 2015 Wiley Periodicals, Inc. Mass Spec Rev 36:255-422, 2017.

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Section: Derivativesmentioning

confidence: 99%

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2011–2012

Harvey

2015

Mass Spectrometry Reviews

View full text Add to dashboard Cite

show abstract

Multi-Glycomics Platform Approach for Cancer

Cited by 1 publication

References 10 publications

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2011–2012

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2011–2012

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