2024
DOI: 10.1101/2024.03.18.585492
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Multi-task deep latent spaces for cancer survival and drug sensitivity prediction

Teemu J. Rintala,
Francesco Napolitano,
Vittorio Fortino

Abstract: MotivationCancer is a very heterogeneous disease that can be difficult to treat without addressing the specific mechanisms driving tumour progression in a given patient. High-throughput screening and sequencing data from cancer cell-lines has driven many developments in drug development, however, there are important aspects crucial to precision medicine that are often overlooked, namely the inherent differences between tumours in patients and the cell-lines used to model themin vitro. Recent developments in tr… Show more

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