Multicenter validation study of the WINROP algorithm as a method for detecting retinopathy of prematurity

Abstract

The WINROP screening algorithm in this study showed moderate sensitivity, so many ROP cases amenable to treatment were not detected. Other criteria should be added to the algorithm to increase the sensitivity.

Algorithm for predicting threshold retinopathy of prematurity is insufficient and fundus examinations are still needed before 31 weeks

“…The point at which high‐risk alarms were triggered, the time between alarm triggers and treatment and the performance of WINROP were consistent with several studies . Unlike the initial validation papers , our study showed that WINROP was not perfect for screening threshold ROP and these findings agreed with a paper published in 2018 . Thus, with regard to the limits of gestational age and birth weight in the new but unpublished French guidelines on screening, we confirm that fundus examination remains necessary for infants born before 31 weeks of gestation or with birth weight of up to 1250 g. Nevertheless, the absence of WINROP triggering may allow waiving fundus examination for infants born at 31 weeks of gestation onwards or with birth weight of 1251 g or more.…”

The Use of Postnatal Weight Gain Algorithms to Predict Severe or Type 1 Retinopathy of Prematurity

“…The full text was read for eligibility, of which 61 were included in the final analysis. The 61 studies (>37 000 infants) included WINROP (n = 36), 6 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 G-ROP (n = 9), 7 , 42 , 56 , 57 , 58 , 59 , 60 , 61 PINT ROP (n = 1), 8 CHOP ROP (n = 6), 9 , 30 , 55 , 62 , 63 , 64 ROPScore (n = 5), 10 , 30 , 55 , 65 , 66 and CO-ROP (n = 4). 11 , 67 , 68 , …”

“…The full text was read for eligibility, of which 61 were included in the final analysis. The 61 studies (>37 000 infants) included WINROP (n = 36), G-ROP (n = 9), PINT ROP (n = 1), CHOP ROP (n = 6), ROPScore (n = 5), and CO-ROP (n = 4) . Studies that used a different cutoff score for ROPScore were not included in the analysis …”