Multicomponent cyclization with azides to synthesize N-heterocycles

Guo, Hong; Zhou, Bei; Chang, Jingjing; Chang, Wenxu; Feng, Jiyao; Zhang, Zhenhua

doi:10.1039/d3ob01115a

Org. Biomol. Chem.

2023

DOI: 10.1039/d3ob01115a

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Multicomponent cyclization with azides to synthesize N-heterocycles

Hong Guo,

Bei Zhou,

Jingjing Chang

et al.

Abstract: Heterocyclic compounds, both naturally derived and synthetically produced, constitute a wide variety of biologically active and industrially important compounds. The synthesis and application of heterocyclic compounds have garnered significant attention...

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2024

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Cited by 2 publications

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Cobalt‐Catalyzed Synthesis of Functionalized Nordazepams and Benzimidazoquinazolines and Their Photophysical Properties

Suresh,

Keerthana,

Khan

2024

Asian J Org Chem

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An efficient and environmentally friendly one‐pot sequential synthesis of functionalized nordazepam and a benzimidazoquinazoline analogue is reported, utilizing cobalt as the metal catalyst. The reaction proceeds via either the α‐alkenylation or dehydrogenative sp3 C‐H functionalization pathway. This transformation includes mild reaction conditions, operational simplicity, and good functional group tolerance. Additionally, this method is suitable for the gram‐scale synthesis of functionalized nordazepam and benzimidazoquinazoline compounds. Furthermore, the synthetic utility, photophysical properties and real‐life application of the synthesized derivatives were explored.

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Cobalt‐Catalyzed Synthesis of Functionalized Nordazepams and Benzimidazoquinazolines and Their Photophysical Properties

Suresh,

Keerthana,

Khan

2024

Asian J Org Chem

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2-Azidoazirines suitable for click chemistry: synthesis of 1-(2H-azirin-2-yl)-1H-1,2,3-triazoles

Golubev,

Simdianov,

Smetanin

et al. 2024

New J. Chem.

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Multicomponent cyclization with azides to synthesize N-heterocycles

Abstract: Heterocyclic compounds, both naturally derived and synthetically produced, constitute a wide variety of biologically active and industrially important compounds. The synthesis and application of heterocyclic compounds have garnered significant attention...

Cited by 2 publications

References 146 publications

Cobalt‐Catalyzed Synthesis of Functionalized Nordazepams and Benzimidazoquinazolines and Their Photophysical Properties

Cobalt‐Catalyzed Synthesis of Functionalized Nordazepams and Benzimidazoquinazolines and Their Photophysical Properties

2-Azidoazirines suitable for click chemistry: synthesis of 1-(2H-azirin-2-yl)-1H-1,2,3-triazoles

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