Multidimensional (0D-3D) nanostructures for lung cancer biomarker analysis: Comprehensive assessment on current diagnostics

Ramanathan, Santheraleka; Gopinath, Subash C.B.; Arshad, M. K. Md; Poopalan, P.

doi:10.1016/j.bios.2019.111434

Cited by 47 publications

(22 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Constructing a solid 3D network is an important strategy for obtaining new and stable graphene nanocomposites that are free of restacking and have many advantageous properties, e.g., high surface area, accessible inner space, tunable electronic properties, better mechanical stability, and enhanced conductivity/electrocatalytic properties. These properties make such 3D architectures suitable for efficient and selective biosensing applications ( Kim et al, 2017 ; Lu, 2018 ; Passaretti et al, 2019 ; Ramanathan et al, 2019 ; Vermisoglou et al, 2020 ).…”

Section: Carbon-based Nanomaterialsmentioning

confidence: 99%

Human virus detection with graphene-based materials

Vermisoglou

Panáček

Jayaramulu

et al. 2020

Biosensors and Bioelectronics

161

117

View full text Add to dashboard Cite

Our recent experience of the COVID-19 pandemic has highlighted the importance of easy-to-use, quick, cheap, sensitive and selective detection of virus pathogens for the efficient monitoring and treatment of virus diseases. Early detection of viruses provides essential information about possible efficient and targeted treatments, prolongs the therapeutic window and hence reduces morbidity. Graphene is a lightweight, chemically stable and conductive material that can be successfully utilized for the detection of various virus strains. The sensitivity and selectivity of graphene can be enhanced by its functionalization or combination with other materials. Introducing suitable functional groups and/or counterparts in the hybrid structure enables tuning of the optical and electrical properties, which is particularly attractive for rapid and easy-to-use virus detection. In this review, we cover all the different types of graphene-based sensors available for virus detection, including, e.g., photoluminescence and colorimetric sensors, and surface plasmon resonance biosensors. Various strategies of electrochemical detection of viruses based on, e.g., DNA hybridization or antigen-antibody interactions, are also discussed. We summarize the current state-of-the-art applications of graphene-based systems for sensing a variety of viruses, e.g., SARS-CoV-2, influenza, dengue fever, hepatitis C virus, HIV, rotavirus and Zika virus. General principles, mechanisms of action, advantages and drawbacks are presented to provide useful information for the further development and construction of advanced virus biosensors. We highlight that the unique and tunable physicochemical properties of graphene-based nanomaterials make them ideal candidates for engineering and miniaturization of biosensors.

show abstract

Section: Carbon-based Nanomaterialsmentioning

confidence: 99%

Human virus detection with graphene-based materials

Vermisoglou

Panáček

Jayaramulu

et al. 2020

Biosensors and Bioelectronics

161

117

View full text Add to dashboard Cite

show abstract

“…Two-dimensional nanomaterials are classified as nanoplates, nanosheets, nano-disks, and nano-prisms. A thick graphene oxide nanosheet coated with gold nanoparticles has been used to identify cancer cell protein biomarkers (Ramanathan et al, 2019). Polymer-coated graphene oxide nanosheets have demonstrated biological properties against gram-positive and negative bacteria (Mahmoudi et al, 2016).…”

Section: Defining Nanostructuresmentioning

confidence: 99%

Modern World Applications for Nano-Bio Materials: Tissue Engineering and COVID-19

Melchor-Martínez

Castillo

Macías-Garbett

et al. 2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Over the past years, biomaterials-based nano cues with multi-functional characteristics have been engineered with high interest. The ease in fine tunability with maintained compliance makes an array of nano-bio materials supreme candidates for the biomedical sector of the modern world. Moreover, the multi-functional dimensions of nano-bio elements also help to maintain or even improve the patients’ life quality most securely by lowering or diminishing the adverse effects of in practice therapeutic modalities. Therefore, engineering highly efficient, reliable, compatible, and recyclable biomaterials-based novel corrective cues with multipurpose applications is essential and a core demand to tackle many human health-related challenges, e.g., the current COVID-19 pandemic. Moreover, robust engineering design and properly exploited nano-bio materials deliver wide-ranging openings for experimentation in the field of interdisciplinary and multidisciplinary scientific research. In this context, herein, it is reviewed the applications and potential on tissue engineering and therapeutics of COVID-19 of several biomaterials. Following a brief introduction is a discussion of the drug delivery routes and mechanisms of biomaterials-based nano cues with suitable examples. The second half of the review focuses on the mainstream applications changing the dynamics of 21st century materials. In the end, current challenges and recommendations are given for a healthy and foreseeable future.

show abstract

“…Up to now, various 0D nanomaterials have been extensively explored. For instance, graphene quantum dots (GQDs) (Qian et al, 2014;Lu et al, 2018;Yan et al, 2019), carbon quantum dots (CQDs) (Zheng et al, 2015;Li et al, 2018b;Pandit et al, 2019), fullerenes (Barberis et al, 2015;, inorganic quantum dots (QDs) (Freeman et al, 2012;Li et al, 2018a;Robidillo et al, 2019), magnetic nanoparticles (MNPs) (Yu et al, 2017;Bragina et al, 2019), noble metal nanoparticles (Yang C. T. et al, 2016;Jain and Chauhan, 2017;Bagheri et al, 2018), upconversion nanoparticles (UCNPs) (Cheng Z. H. et al, 2019;Gu et al, 2019) and polymer dots (Pdots) (Ou et al, 2019; are all representative 0D nanomaterials with potential applications in materials science (Zhang X. et al, 2014), photovoltaic science (Guo et al, 2010), catalysis (Xu et al, 2015), energy (Guldi and Sgobba, 2011), sensing (Ramanathan et al, 2019), biomedicine (Yao et al, 2018) and nanodevices (Zhang Y. et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Application of Zero-Dimensional Nanomaterials in Biosensing

et al. 2020

View full text Add to dashboard Cite

Zero-dimensional (0D) nanomaterials, including graphene quantum dots (GQDs), carbon quantum dots (CQDs), fullerenes, inorganic quantum dots (QDs), magnetic nanoparticles (MNPs), noble metal nanoparticles, upconversion nanoparticles (UCNPs) and polymer dots (Pdots), have attracted extensive research interest in the field of biosensing in recent years. Benefiting from the ultra-small size, quantum confinement effect, excellent physical and chemical properties and good biocompatibility, 0D nanomaterials have shown great potential in ion detection, biomolecular recognition, disease diagnosis and pathogen detection. Here we first introduce the structures and properties of different 0D nanomaterials. On this basis, recent progress and application examples of 0D nanomaterials in the field of biosensing are discussed. In the last part, we summarize the research status of 0D nanomaterials in the field of biosensing and anticipate the development prospects and future challenges in this field.

show abstract

Multidimensional (0D-3D) nanostructures for lung cancer biomarker analysis: Comprehensive assessment on current diagnostics

Cited by 47 publications

References 78 publications

Human virus detection with graphene-based materials

Human virus detection with graphene-based materials

Modern World Applications for Nano-Bio Materials: Tissue Engineering and COVID-19

Application of Zero-Dimensional Nanomaterials in Biosensing

Contact Info

Product

Resources

About