2017
DOI: 10.1063/1.4976780
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Multifunctional microsphere formulation of fluorescent magnetic properties for drug delivery system

Abstract: Abstract. The microsphere formulations of Chit/TPP/Sm/Fe3O4/Rn were prepared by an ionic gelation technique, where Chit = chitosan, TPP = tripolyphosphate, Sm = samarium and Rn = ranitidine. Optimum of microsphere formulation exhibit magnetic and fluorescent properties with adsorption efficiency of ~92% was obtained for Chit/TPP/Sm/Fe3O4/Rn with ratio 400:500:50:1:20. Fluorescence intensity of microsphere formulations increased with the cumulative amount release of ranitidine, so that the changing of fluoresce… Show more

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“…The microsphere formulations of Chit/TPP/Sm/Fe 3 O 4 /Rn were also prepared by an ionic gelation technique, where Chito = chitosan, TPP = tripolyphosphate, Sm = samarium and Rn = ranitidine. This microsphere formulation was found to exhibit excellent magnetic and fluorescent properties [82].…”
Section: Multimodal Bioimagingmentioning
confidence: 99%
“…The microsphere formulations of Chit/TPP/Sm/Fe 3 O 4 /Rn were also prepared by an ionic gelation technique, where Chito = chitosan, TPP = tripolyphosphate, Sm = samarium and Rn = ranitidine. This microsphere formulation was found to exhibit excellent magnetic and fluorescent properties [82].…”
Section: Multimodal Bioimagingmentioning
confidence: 99%
“…Magnetic drug delivery microsphere is a new targeted drug delivery system and has been studied extensively in recent years [ 40 , 41 , 42 , 43 ]. Magnetic drug microspheres are mainly composed of magnetic materials, biocompatible materials and drugs.…”
Section: Introductionmentioning
confidence: 99%