Multifunctional nanoparticles/silica microsphere assemblies using polyglycidyl methacrylate shells as supports

Versatile Multi-Functional Block Copolymers Made by Atom Transfer Radical Polymerization and Post-Synthetic Modification: Switching from Volatile Organic Compound Sensors to Polymeric Surfactants for Water Rheology Control via Hydrolysis

“…Several polymeric architectures can be obtained by reaction with compounds with different degrees of functionalization, to yield, for example, star and linear polymers [17,18]. Polymeric derivatives of GMA were found able to interact with metal ions, polar and non-polar biomolecules, allowing the construction of drug delivery system with controlled release as function of external stimuli [19,20]. Cross-linked GMA micelles were used as reactors for the synthesis of nanoparticles [21].…”

“…Recently, GMA epoxide rings have been functionalized with fluorophores to enable investigation by light emission stimuli-induced structural modifications. Pyrene, Coumarin and Rhodamine B were successfully used to grant to various GMA derivatives emitting properties [16,19,20,21]. Among those, pyrene derivatives has been widely investigated as molecular probes in micellar aggregates or even in the investigation of structural and conformation changes in proteins [22], as a result of its aggregation-induced quenched fluorescence.…”

Synthesis of magnetic and fluorescent multifunctional hollow silica nanocomposites for live cell imaging

“…For example, Wang et al reported a method to make various types of nanoparticles, including CdTe quantum dots, Au nanoparticles and Fe 3 O 4 nanoparticles, assemble on silica microspheres. The properties of the assembled nanoparticles were well retained in the nanocomposite assemblies, and the controllable integration of magnetic and fluorescent properties was achieved [14]. Veronica and his co-workers described a synthesis of composite silica spheres with magnetic and luminescent functionalities by a modified Stö-ber's method combined with layer-by-layer assembly technique [15].…”

Self-assembly and applications of poly(glycidyl methacrylate)s and their derivatives

“…118,119 Yang et al reported multifunctional microsphere assemblies with magnetic and fluorescent properties, where the PGMA shells, grown on silica microspheres using the surface-initiated ATRP technique, served as bridges to interact with CdTe quantum dots, Au and oil-soluble Fe 3 O 4 nanoparticles. 120 Liu et al prepared PGMA-coated silica nanoparticles using the same method followed by CdTe coupling through the ringopening reaction of epoxy groups. 121 A biomolecule, the human antirabbit tumor necrosis factor-alpha (TNF-a) antibody, was also attached to CdTe quantum dots-coated silica nanoparticles for TNF-a detection.…”