Denote by T and I α the bilinear Calderón-Zygmund operator and bilinear fractional integrals, respectively. In this paper we give the boundedness and compactness of the commutators [T , b] and compact operators (if b ∈ CMO, the BMO-closure of C ∞ c ) from L p 1 ,λ 1 × L p 2 ,λ 2 to L p,λ for some suitable indexes λ, λ 1 , λ 2 and p, p 1 , p 2 . As an application of our results, we give also the boundedness and compactness of the commutators formed by the bilinear pseudodifferential operators on Morrey spaces.