“…8,9 Furthermore, it has been shown to predict subsequent macrocalcification as well as progression of coronary artery calcification (CAC) scores. 10 Moreover, 18 F-NaF uptake is increased in culprit coronary and carotid plaques in the setting of adverse CV events, predicts restenosis following endovascular intervention for peripheral arterial disease, and predicts progression of aortic stenosis. [3][4][5][6] In a recent study, coronary 18 F-NaF uptake was shown to independently predict future myocardial infarctions in individuals with stable CAD beyond standard risk assessment modalities including CAD risk scores, CAC, as well as angiographic burden and severity of CAD.…”