Multimodality Imaging, including Dual-Energy CT, in the Evaluation of Gallbladder Disease

Ratanaprasatporn, Lisa; Uyeda, Jennifer W.; Wortman, Jeremy R.; Richardson, Ian J.; Sodickson, Aaron

doi:10.1148/rg.2018170076

Cited by 71 publications

(34 citation statements)

References 67 publications

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“…As in our case, the relevant contribution of spectral CT has been demonstrated in the literature with a similar or a reduced radiation dose as compared to conventional CT [11,12]. In such acute conditions, MRI is not the preferred method for the diagnosis of acute cholecystitis, but may contribute to detect entrapped choledocholithiasis and its related complications [10].…”

Section: Discussionsupporting

confidence: 61%

“…In the daily practice, US is still the primary imaging modality when GBS and acute cholecystitis are suspected [1,2]. In an acute setting, doubtful or difficult cases on US are evaluated additionally with CT [10]. As in our case, the relevant contribution of spectral CT has been demonstrated in the literature with a similar or a reduced radiation dose as compared to conventional CT [11,12].…”

Section: Discussionmentioning

confidence: 62%

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Spectral CT Detection of Entrapped Gallstone Based on Z-effective Map

Danse

Jamali²,

Hubert³

2018

Journal of the Belgian Society of Radiology

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of gallbladder stone (GBS) is based on ultrasound (US), due to its high accuracy (98%) [1]. When cholecystitis is clinically suspected, US is also the preferred first diagnostic method, to identify signs of inflammation and the causative stone [2]. In inconclusive cases, computed tomography (CT) can be required to confirm or exclude cholecystitis, with a lower accuracy for stone detection, ranging from 25-88 % [3]. The most recent spectral CT systems (dual-energy or spectral systems) are based on the principle of image acquisition at two levels of energy (80 and 140 kVp). In vitro studies dedicated to GBS have demonstrated that higher voltages could help CT to detect more GBS. Some CT manufacturers have developed software solutions giving access to mean atomic number values of anatomic structures. Here we present a case of a patient with a final and diagnosis of entrapped gallstone causing subacute cholecystitis. This was detected first with spectral CT and the use of the mean atomic number display map of the gallbladder content.

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Section: Discussionsupporting

confidence: 61%

Section: Discussionmentioning

confidence: 62%

Spectral CT Detection of Entrapped Gallstone Based on Z-effective Map

Danse

Jamali²,

Hubert³

2018

Journal of the Belgian Society of Radiology

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“…Over the past few decades, ultrasonography was considered as one of the most important imaging modality for detection of gallbladder diseases. However, it is limited in the diagnosis of early lesion because of the lower sensitivity and specificity [ 3 ]. Recently, diffusion weighted imaging (DWI) has been reported to facilitate the diagnosis of gallbladder cancer, and it can also differentiate gallbladder benign and malignant disorders [ 4 – 6 ].…”

Section: Introductionmentioning

confidence: 99%

Gallbladder carcinoma: an initial clinical experience of reduced field-of-view diffusion-weighted MRI

Zou

Wang

et al. 2020

Cancer Imaging

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Background: The purpose of this study is to compare the diagnostic value, imaging quality and apparent diffusion coefficient (ADC) value of reduced field-of-view diffusion-weight imaging (r-FOV DWI) and full field-of-view diffusion-weight imaging (f-FOV DWI) in patients with gallbladder carcinoma and other lesions of gallbladder. Methods: Two hundred ninety-six patients with gallbladder diseases underwent both r-FOV DWI and f-FOV DWI on a 3.0 T MRI scanner. Two radiologists assessed subjective image quality parameters independently. The Wilcoxon signed-rank test was used to compare subjective qualitative image score. Objective quality values and the mean ADC values were analyzed by paired t-test. The correlation between pathological results and mean ADC value were estimated using Spearman rank correlation analysis. Results: The CNR value (10.23 ± 2.92) and image quality score (13.84 ± 1.07) of r-FOV DWI were significantly higher than those of f-FOV DWI (5.24 ± 1.29 P<0.001; 10.41 ± 1.11 P<0.001). There was no significant difference between mean ADC values of the two DWI sequences for all three groups (Group 1, chronic cholecystitis; Group 2, benign lesions of gallbladder; Group 3, gallbladder carcinoma. P = 0.239, 0.974 and 0.226 respectively). For both DWI sequences, the mean ADC values were the highest in the group of cholecystitis and the lowest in the group of gallbladder carcinoma (2.49 ± 0.14 vs 1.49 ± 0.12; 2.50 ± 0.14 vs 1.50 ± 0.13, for f-FOV and r-FOV respectively), the differences among groups were statistically significant (P<0.01). The mean ADC values for both DWI sequences were negatively correlated with the group number, which increased with the malignant tendency of lesions (r = − 0.892, P<0.01; r = − 0.913, P<0.01 for f-FOV and r-FOV respectively). Conclusion: Reduced Field-of-view Diffusion-weighted MRI is a good tool to diagnosis the gallbladder carcinoma, with better image quality and without affecting ADC values.

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“…The utility of MRI as a noninvasive method in detecting gallstones is well established previously, and it clearly outperforms US and CT in depicting ductal stones [23][24][25]. Compared to MRI, abdominal US has also limitations sometimes due to bowel gas or patient's obesity.…”

Section: Discussionmentioning

confidence: 93%

Diagnostic Potential of Magnetic Resonance Imaging in Chronic Abdominal Pain

et al. 2019

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Introduction: About half of the adult patients suffering from chronic abdominal pain may have no organ-related cause. Our purpose was to evaluate the additional information of magnetic resonance imaging (MRI) in diagnosing the underlying organic causes of such pain. Methods: We performed retrospective audit of 636 consecutive abdominal MRI in patients suffering from nonspecific abdominal pain (NSAP) during years 2014-2017. Medical history, clinical examination, endoscopy reports, and the results of MRI were compared in all patients. The hypothesis was that MRI increases markedly the diagnostic specificity of patients' symptoms. Results: The mean age of patients was 66 ± 14 years and 60 percent were females. Duration of abdominal pain ranged from 1 month to 30 years (median 1.1 ± 4.0 years). Concurrently with abdominal MRI (n = 636), also ultrasound (n = 106, 17%), colonoscopy (n = 222, 35%), and gastroscopy (n = 217, 34%) were performed. Abdominal MRI revealed additional information in 161/636 (25%) of NSAP patients. Spinal and pelvic bone abnormalities (n = 107) and malignant tumors (n = 31) were the most significant organ-specific findings changing the treatment algorithm. Conclusions: When computerized tomography is not available in outpatient clinics, abdominal MRI increases markedly diagnostic specificity and alters the treatment in 1 of 4 patients suffering from NSAP. Abdominal MRI is therefore suggested for patients suffering from severe symptoms of NSAP.

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Multimodality Imaging, including Dual-Energy CT, in the Evaluation of Gallbladder Disease

Cited by 71 publications

References 67 publications

Spectral CT Detection of Entrapped Gallstone Based on Z-effective Map

Spectral CT Detection of Entrapped Gallstone Based on Z-effective Map

Gallbladder carcinoma: an initial clinical experience of reduced field-of-view diffusion-weighted MRI

Diagnostic Potential of Magnetic Resonance Imaging in Chronic Abdominal Pain

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