Multiple and extensive lichen planus‐like keratoses: an underestimated cutaneous eruption observed in patients with intense sun damage

Abstract

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Lichen planus‐like keratosis emerging in a pediatric case of xeroderma pigmentosum group A

“…related to chronic UV exposure and it is common in Caucasians, but infrequent in Asians because lighter skinned individuals are more prone to develop this condition than darker skinned subjects. 3 LPLK generally resolves spontaneously 2 and the lesion in our case disappeared 6 months after performance of a skin biopsy. This XP-A case may suggest that the induction of LPLK may be related to the accumulation of skin photodamage due to a decreased ability to repair UV-induced DNA damage.…”

Diffuse lichen planus-like keratoses and clinical pseudo-progression associated with avelumab treatment for Merkel cell carcinoma, a case report

“…Classic LPLK usually present as well-demarcated violaceous to brown, scaly papules or small plaques located on the trunk or extremities, often in middle-aged, fair-skinned women. They almost always occur as a solitary lesion, but have infrequently been reported in a diffuse pattern, particularly in the setting of extensive solar damage [9, 10]. When LPLK manifest as numerous lesions, careful consideration should be given regarding a diagnosis of lichen planus and physical examination findings combined with natural history can help distinguish the two.…”

Multiple lichen planus‐like keratoses: Lichenoid drug eruption simulant and under‐recognised cause of pruritic eruptions in the elderly

“…In a study of 1040 cases, 8% of patients had two lesions and less than 1% had three. Infrequent reports of the eruption of numerous lesions have emphasised the difficulties in differentiating multiple LPLK from other eruptions such as lichen planus, Grover's disease, folliculitis, disseminated superficial actinic porokeratosis, actinic keratoses and drug‐induced photo‐dermatoses both clinically and histologically. The following six cases (Table ) are representative of a larger cohort noted over a 9‐month period in a solo dermatology practice, illustrating that multiple LPLK are relatively common and frequently cause diagnostic difficulties.…”