Multiple cranial nerve palsies and COVID‐19 vaccination

Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj

doi:10.1111/ane.13561

Cited by 1 publication

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References 4 publications

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“…They include acute ischemic stroke, intracranial hemorrhages, and cerebral venous sinus thrombosis. [78,80] Other reported neuro-ophthalmic complications include: bilateral arteritic anterior ischemic optic neuropathy (AAION), [81] post-vaccination cranial neuropathy, that is, third [73] and sixth [82][83][84] nerve palsies, facial palsy, [84][85][86][87] multiple cranial nerve palsies, [88] pupillary abnormalities such as Horner's syndrome, Holmes-Adie pupil, miosis and mydriasis, [78] eight nerve involvement and benign paroxysmal positional vertigo, [89] and post-vaccination optic neuritis. [90][91][92] In multiple sclerosis patients, BNT162b2 mRNA vaccine was reported to be associated with a transient increase of MS symptoms in 3.8% but none of them needed treatment.…”

Section: Neuro-ophthalmic Complications Of Covid-19 Vaccinesmentioning

confidence: 99%

Neuro-ophthalmic Manifestations of Coronavirus Disease 2019 and Its Vaccination: A Narrative Review

Feizi

Isen

Tavakoli

2023

JOVR

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Coronavirus disease 2019 (COVID-19) is a current pandemic caused by SARS-CoV-2 that has vastly affected the whole world. Although respiratory disease is the most common manifestation of COVID-19, the virus can affect multiple organs. Neurotropic aspects of the virus are increasingly unfolding, in so far as some respiratory failures are attributed to brainstem involvement. The neuro-ophthalmic manifestations of COVID-19 and the neuro-ophthalmic side effects of vaccination were reviewed. The major findings are that the SARS-CoV-2 infection commonly causes headaches and ocular pain. It can affect the afferent and efferent visual pathways by ischemic or inflammatory mechanisms. Optic nerve may be the origin of transient or permanent visual loss from papillophlebitis, idiopathic intracranial hypertension, or optic neuritis. Cerebrovascular strokes are not uncommon and may lead to cortical visual impairment or optic nerve infarction. SARSCoV- 2 may affect the pupillomotor pathways, resulting in tonic pupil (Adie’s syndrome) or Horner’s syndrome. Cranial neuropathies including third, fourth, sixth, and seventh nerve palsies have all been reported. Rhino-orbital mucormycosis superinfections in COVID-19 patients receiving steroids or other immunosuppressive therapies may result in unilateral or bilateral visual loss and ophthalmoplegia. Autoimmune conditions such as Guillain- Barré, Miller-Fisher syndrome, and ocular myasthenia have been reported.

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