Abstract:Data available for 175 families with maternal isoimmunization to red blood cell antigens, exclusive of A, B, and R b , were analyzed for interaction of un-~ ~~ ~
“…Our finding that ABO incompatibility also protects against non‐D immunizations is in line with early studies of Levine, reporting on a protective effect on c and K immunizations . Later, Stern also postulated an effect of ABO incompatibility on other types of immunization, although the possible influence of a previous blood transfusion was not completely clear in this study.…”
We found that ABO incompatibility and RhIG reduce the risks not only for D, but also for non-Rh immunizations, suggesting that antibody-mediated immune suppression in this condition is not antigen specific.
“…Our finding that ABO incompatibility also protects against non‐D immunizations is in line with early studies of Levine, reporting on a protective effect on c and K immunizations . Later, Stern also postulated an effect of ABO incompatibility on other types of immunization, although the possible influence of a previous blood transfusion was not completely clear in this study.…”
We found that ABO incompatibility and RhIG reduce the risks not only for D, but also for non-Rh immunizations, suggesting that antibody-mediated immune suppression in this condition is not antigen specific.
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