Multiple Endoscopic Polypectomies for Schistosomal Polyposis of the Colon

Hussein, A T; Magd, A.M. Abou El; Medany, S.; Sherif, S M; Williams, C. B.

doi:10.1016/s0140-6736(83)91969-4

Cited by 12 publications

(4 citation statements)

References 5 publications

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“…Colonoscopic polypectomy is safe and effective and may be required along with medical therapy to achieve complete symptom relief and prevent complications. All symptomatic or large polyps should be removed after pharmacologic treatment even before waiting for complete parasitological cure because they will not resolve with medical treatment alone [33,34,68,69] .…”

Section: Treatmentmentioning

confidence: 99%

Hepatic and Intestinal Schistosomiasis: Review

Elbaz

Esmat

2013

Journal of Advanced Research

183

176

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Schistosomiasis is an endemic disease in Egypt caused by the trematode Schistosoma which has different species. Hepatic schistosomiasis represents the best known form of chronic disease with a wide range of clinical manifestations. The pathogenesis of schistosomiasis is related to the host cellular immune response. This leads to granuloma formation and neo angiogenesis with subsequent periportal fibrosis manifested as portal hypertension, splenomegaly and esophageal varices. Intestinal schistosomiasis is another well identified form of chronic schistosomal affection. Egg deposition and granuloma formation eventually leads to acute then chronic schistosomal colitis and is commonly associated with polyp formation. It frequently presents as abdominal pain, diarrhea, tenesmus and anal pain. Definite diagnosis of schistosomiasis disease depends on microscopy and egg identification. Marked progress regarding serologic diagnosis occurred with development of recent PCR techniques that can confirm schistosomal affection at any stage. Many antischistosomal drugs have been described for treatment, praziquantel being the most safe and efficient drug. Still ongoing studies try to develop effective vaccines with identification of many target antigens. Preventive programs are highly needed to control the disease morbidity and to break the cycle of transmission.

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Section: Treatmentmentioning

confidence: 99%

Hepatic and Intestinal Schistosomiasis: Review

Elbaz

Esmat

2013

Journal of Advanced Research

183

176

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“…Endoscopic polypectomy can be pursued in cases of residual polyps. Elimination of polyps has been shown to dramatically improve anemia and hypoalbuminemia [56].…”

Section: Intestinal Schistosomiasismentioning

confidence: 99%

Gastrointestinal complications of schistosomiasis

Schafer

Hale²

2001

Curr Gastroenterol Rep

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Schistosomiasis is an important disease in many parts of the world and has affected the course of human history many times over. The parasitic infection is acquired during contact with infected water. A chronic inflammatory response to schistosome eggs, mediated by both cellular and humoral mechanisms, is the root of the pathology seen in schistosomiasis. Hepatosplenic disease results in intrahepatic presinusoidal portal hypertension. The resultant esophageal and gastric varices are an important cause of morbidity and mortality. Standard treatment guidelines for managing varices can be applied to patients with schistosomiasis. Coinfection with viral hepatitis results in liver disease that progresses more rapidly and is more difficult to treat. Intestinal schistosomiasis may be confused with other disease states and can be an important cause of morbidity, especially in heavily infected patients. Diagnosis relies on demonstration of schistosome eggs in feces or tissue. Praziquantel is the treatment of choice. The development of a vaccine for schistosomiasis is an important goal in the attempt to control this disease.

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“…Although nonspecific, colonoscopy may provide valuable information in the diagnosis of colonic schistosomiasis, such as edematous, congestive mucosa and petechial hemorrhages in patients with acute schistosomal colitis, and a dense vascular mesh with more close-set, flat or elevated, yellow nodules and polyps, and intestinal stricture in patients with chronic schistosomal colitis [4]. To achieve complete symptom relief and prevent complications, colonoscopic polypectomy may be required along with medical therapy [5]. This document was downloaded for personal use only.…”

mentioning

confidence: 99%