Multiple Epidermolytic Acanthomas on the Scrotum: What Genital Pruritus Can Reveal

Response of pruritic scrotal epidermolytic acanthomas to pimecrolimus 1% cream

“…We believe this was the case in our patient, judging by the sustained trauma produced by repeated scratching of the scrotum. However, as observed in several reports in the literature, EA lesions might themselves be pruritic [4][5][6][7]. In any case, physicians should aim to treat pruritus in these patients to avoid perpetuation of both pruritus and lesions.…”

“…Not uncommonly, their clinical appearance in the anogenital area might lead to misdiagnosis as other lesions that commonly develop at this site, such as condylomata acuminate [2,3]. Although mainly asymptomatic, EA occasionally presents with pruritus [4][5][6]. We report a patient with pruritic scrotal EA successfully treated with topical pimecrolimus.…”