Multiple eruptive clear cell acanthomas successfully treated with CO2 laser ablation

Drumm, Claire; Ngan, Kok; Crema, Juliano; Khirwadkar, Nitin; Defty, Charlotte; Eustace, Karen

doi:10.1080/09546634.2022.2049587

Cited by 2 publications

(6 citation statements)

References 6 publications

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“…Most commonly CCA appears as a solitary lesion. However, there are reports of rare cases of multiple disseminated eruptive CCAs, which are characterized by the presence of more than 30 lesions progressively appearing over time 3–6 . Notably, Innocenzi et al 7 observed about 400 CCAs in a young female.…”

Section: Discussionmentioning

confidence: 99%

“…However, there are reports of rare cases of multiple disseminated eruptive CCAs, which are characterized by the presence of more than 30 lesions progressively appearing over time. [3][4][5][6] Notably, Innocenzi et al 7 observed about 400 CCAs in a young female. However, generalized eruptive CCAs have not been reported so far.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 Disseminated eruptive CCAs have very rarely been reported. [3][4][5][6][7] We here describe a patient with generalized eruptive CCAs.…”

Section: Introductionmentioning

confidence: 99%

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Generalized eruptive clear cell acanthomas

Gambichler

Heinzer²,

Kautz³

et al. 2023

JEADV Clinical Practice

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In most cases, clear cell acanthoma (CCA) is an uncommon solitary lesion with distinctive clinicopathological features. We report the case of an 80‐year‐old man with generalized asymptomatic skin lesions predominantly affecting his chest, abdomen and his legs. On dermoscopy, the lesions showed dotted vessels in a linear pearl‐like distribution (“pearl necklace”) surrounded by a slightly whitish halo. Histopathology clearly confirmed the diagnosis of CCA. In conclusion, CCA being an uncommon solitary skin lesion may also appear in very rare cases as a generalized eruptive skin condition.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Generalized eruptive clear cell acanthomas

Gambichler

Heinzer²,

Kautz³

et al. 2023

JEADV Clinical Practice

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“…However, GM patients treated with cauterising solution and antibiotics frequently exhibit symptomatic recurrence and tympanic perforation 2,3 . CO 2 laser vaporisation has been widely used in removing keloids, acanthoma and neurofibromas 5–7 . CO 2 laser vaporisation was introduced in GM treatment in 2002, 8 and the low incidence of complications emphasises the potential of CO 2 laser vaporisation in curing GM 9 .…”

Section: Introductionmentioning

confidence: 99%

“…2,3 CO 2 laser vaporisation has been widely used in removing keloids, acanthoma and neurofibromas. [5][6][7] CO 2 laser vaporisation was introduced in GM treatment in 2002, 8 and the low incidence of complications emphasises the potential of CO 2 laser vaporisation in curing GM. 9 However, the outcomes of long-term follow-up of CO 2 laser vaporisation in GM remain unclear.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of carbon dioxide laser and caustic agent cauterisation for the focal granular myringitis: A randomised trial

Kuo¹,

Luo²,

2023

Clinical Otolaryngology

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Objectives: Granular myringitis (GM) is a troublesome disease with a high incidence of recurrence and relapse. CO 2 laser vaporisation and trichloroacetic acid (TAA) have been applied in treating several otological diseases, both with favourable therapeutic efficacy. However, long-term therapeutic efficacy of both CO 2 laser vaporisation and TAA cauterisation against GM has not yet been evaluated. We aimed to investigate the therapeutic potential of CO 2 laser vaporisation and TAA cauterisation in GM management.Study Design: Prospective and randomised study. Participants: A total of 88 GM patients who failed therapy with boric acid, alcohol and glycerin ear drop otic solution between July 2009 and January 2018 were included. Participants were randomly assigned to receive CO 2 laser vaporisation (n = 39) or TAA cauterisation (n = 49). Main Outcome Measures: Main outcomes were treatment success, complications after 4 months of treatment, and recurrence within 4-12 months after treatment.Results: The success rate was significantly higher in the CO 2 group than in the TAA group (94.9% vs. 77.6%, p = .023). After 4 months of treatment, the GM recurrence rate was comparable between the two groups (13.5% vs. 18.4%, p = .562). The CO 2 laser group had one case of perforation and one case of severe vertigo, whereas one participant in the TAA cauterisation group experienced hearing loss. Conclusion:Both TAA cauterisation and CO 2 laser vaporisation are safe and effective treatments for GM. The success rate of CO 2 laser vaporisation for treating GM is higher than that of TAA cauterisation. Recurrence rates are comparable within 1 year.

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Multiple eruptive clear cell acanthomas successfully treated with CO2 laser ablation

Cited by 2 publications

References 6 publications

Generalized eruptive clear cell acanthomas

Generalized eruptive clear cell acanthomas

Efficacy of carbon dioxide laser and caustic agent cauterisation for the focal granular myringitis: A randomised trial

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