Multiple Eruptive Dermatofibromas Occurring in a Patient with Myelodysplastic Syndrome

Multiple eruptive dermatofibromas and immunosuppression: report of two cases and review of the literature

“…In our review of the literature from 1973 to 2006, we found that 21 of 67 patients were otherwise healthy, while 46 (69%) had an underlying disease. Thirty‐eight cases (83%) of the latter were related to various immunodeficiency states such as systemic lupus erythematous, 3,7,10,13,17,20,22,24,25,28,29,39 dermatomyositis, 50 Sjögren's disease, 17,25,42 HIV infections, 26–28,30,32,33,36,38 pemphigus vulgaris with ulcerative colitis, 20 myasthenia gravis, 16 sarcoidosis, 31 mycosis fungoides, 35 acute and chronic myeloid leukemia, 43,45 myelodysplastic syndrome 44 and kidney transplantation 47,48 . Twenty (43.5%) patients of this group had autoimmune diseases, mostly systemic lupus erythematosus which has been reported in 17 cases.…”

Multiple eruptive myxoid dermatofibromas: report of first case and review of literature

“…31 These include any immunological disorders, lymphoproliferative disorders such as chronic myelogenous leukaemia and myelodysplastic syndrome, metabolic diseases such as diabetes mellitus, obesity and hyperlipidaemia as well as hypertension, that have been reported in association with multiple eruptive dermatofibromas. 6,35,37,38 Interpretation of the clinical, histopathological and immunohistochemical findings in our patient led us to the diagnosis of multiple eruptive myxoid dermatofibromas.…”

“…The reviewed cases, presented in Table 1, 3,6–37 indicate that multiple eruptive dermatofibromas show a slight female predominance (23 of 42, 55%). Lesions were mostly localized on the extremities (41 of 42, 97%), and the trunk was affected in 19 of 42 cases.…”

A Case of Idiopathic Dermatofibromatosis

“…İyatrojenik immünsupresyon vakalarında da MED gelişimi bildirilmiştir. [22][23][24][25][26][27][28] Tablo 1'de literatürde 18 yaş ve altında bildirilen multipl dermatofibrom olguları görül-mektedir. 4,6,[29][30][31] Literatür taranarak elde edilen 18 yaş altı MED tanılı olgular incelendiğinde cinsiyet açısın-dan fark saptanmamış olup, olguların hiçbirinde eşlik eden hastalık veya sistemik tedavi kullanımı bildirilmemiştir.…”