Multiple Factor Analysis of the Autonomous Nervous System during PTCA

Abstract

This study describes the Autonomic Nervous System (ANS) response before, during and after a percutaneous transluminal coronary angioplasty (PTCA). The study population consisted of 37 patients undergoing PTCA from Staff-3 Database. Classical Heart rate variability (HRV) parameters: RR mean, SD, rMSSD, LF, HF, LF/HF and LF/(HF+LF) were extracted and a multiple factorial analysis (MFA) was carried out. Preliminary results show that sympathetic activity increases during and after PTCA, and global HRV decreases during PTCA and increases after PTCA. These findings suggest that MFA provides a powerful tool allowing assessment of ANS's response during PTCA.

Characterization of the nonlinear content of the heart rate dynamics during myocardial ischemia

“…Linear HRV methods have previously been used in short-time PTCA data, indicating an increase of the sympathetic activity during and in the few minutes immediately after the angioplasty [10]. However, linear techniques disregard the nonlinear couplings between the regulatory systems involved in ischemic and reperfusion stages.…”

Multifractal and nonlinear assessment of autonomous nervous system response during transient myocardial ischaemia

“…Manfrini et al (2004) assessed ANS activity during spontaneous and balloon-induced ischaemia by frequency domain heart rate variability (HRV) analysis, showing that balloon inflation and occlusion evoke a parasympathetic predominance, whereas spontaneous episodes of ischaemia produce a sympathetic activation. Other clinical evaluations of HRV during PTCA have been performed (Airaksinen et al 1999, Clariá et al 2002, Castro et al 2005 using standard time and frequency-domain methods to evaluate the influence of sympathetic and parasympathetic activities, or the balance produced by different occlusions during PTCA. Previous studies have already evaluated ANS behaviour during prolonged PTCA using HRV analysis with fractal-like indices (Gomis et al 2006) and multiscale information analysis (MIA) of HRV, taking into account entropy rates (Valencia et al 2007).…”

Multifractal characterization of the autonomous nervous system during prolonged coronary artery occlusion

“…Some clinical evaluations of HRV during PTCA have been reported [3]- [5]. These studies use standard time and frequency-domain methods to evaluate the influence of sympathetic and parasympathetic activity or its balance produced by different occlusions during PTCA.…”