Multiple-Vessel-Based Blood Gas Profiles Analysis Revealed the Potential of Blood Oxygen in Mammary Vein as Indicator of Mammary Gland Health Risk of High-Yielding Dairy Cows

Feng, Juan; Peng, Wenchao; Hu, Zhenzhen; Cai, Jie; Liu, Jianxin; Wang, Diming

doi:10.3390/ani12121484

Cited by 2 publications

(3 citation statements)

References 32 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Blood oxygen concentration was calculated using the following equation [ 22 , 23 ]: oxygen concentration (%) = 0.003 × pO 2 + 1.34 × HGB × sO 2 , where pO 2 is the partial pressure of oxygen (mmHg), HGB is hemoglobin (g/dL), and sO 2 is oxygen saturation (%). The arterio-venous difference (AVD) was calculated according to the method reported previously [ 24 ].…”

Section: Methodsmentioning

confidence: 99%

Heat stress affects dairy cow health status through blood oxygen availability

Zeng,

Cai,

Wang

et al. 2023

J Animal Sci Biotechnol

Self Cite

View full text Add to dashboard Cite

Background Rises in global warming and extreme weather occurrence make the risk of heat stress (HS) induced by high ambient temperatures more likely in high-yielding dairy cows, resulting in low milk quality and yield. In animals, oxygen is involved in many physiological and metabolic processes, but the effects of HS on oxygen metabolism remain unclear. Thus, the current study aimed to investigate how oxygen metabolism plays a role in health status of dairy cows by measuring the milk yield, milk composition, and blood biochemical variables of cows under different levels of HS: none (No-HS), mild (Mild-HS), and moderate HS (Mod-HS). Results The HS significantly increased rectal temperature (Ptreat < 0.01) and respiration rate (Ptreat < 0.01). Under Mod-HS, greater Na+ (P < 0.05) and lower total CO2, and pH (P < 0.05) were observed relative to those under No-HS and Mild-HS. Oxygen concentrations in both coccygeal artery and mammary vein (Ptreat < 0.01) were lower under Mod-HS than under No-HS. Coccygeal vein concentrations of heat shock protein 90 (HSP90) (P < 0.05) increased during Mod-HS compared with those in cows under No-HS. Malondialdehyde increased during Mod-HS, and glutathione peroxidase (P < 0.01) increased during Mild-HS. Coccygeal vein concentrations of vascular endothelial growth factor (P < 0.01), heme oxygenase-1 (P < 0.01), and hypoxia-inducible factor 1α (P < 0.01) were greater in cows under Mod-HS than those under No-HS. Red blood cell count (P < 0.01) and hemoglobin concentration (P < 0.01) were lower in the coccygeal vein of dairy cows under Mild- and Mod-HS than those of cows under No-HS. Conclusions Exposure to HS negatively impacts the health status and lactation performance of dairy cows by limiting oxygen metabolism and transportation. However, the specific mechanism by which HS affects mammary function in cows remains unclear and requires further exploration.

show abstract

Section: Methodsmentioning

confidence: 99%

Heat stress affects dairy cow health status through blood oxygen availability

Zeng,

Cai,

Wang

et al. 2023

J Animal Sci Biotechnol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Several studies have focused on the evaluation of the main alterations during mastitis, with the intention of also extending the use of blood parameters to this disease. The application of an Emogas analyzer would provide the possibility of obtaining prognostic index also in field condition and in real time [36,[61][62][63][64]. Blood gas analysis is already extensively used in the evaluation and management of multiple pathologic condition.…”

Section: Blood Gas Analysismentioning

confidence: 99%

“…The authors analyzed sodium (Na) and potassium (K) in particular, as they are considered to be important indexes for mammary permeability evaluation. The results showed higher levels of K, and a higher ratio of Na to K in animals with high SCC, suggesting the use of blood gas parameters for a rapid evaluation of the mammary gland health status [62]. Additionally, another article of 2016 showed levels of calcium, phosphorous, and zinc were significantly lower in the blood serum of infected cattle than in healthy cattle [69].…”

Section: Blood Gas Analysismentioning

confidence: 99%

Mastitis in Dairy Cattle: On-Farm Diagnostics and Future Perspectives

Tommasoni,

Fiore,

Lisuzzo

et al. 2023

Animals

View full text Add to dashboard Cite

Mastitis is one of the most important diseases in dairy cattle farms, and it can affect the health status of the udder and the quantity and quality of milk yielded. The correct management of mastitis is based both on preventive and treatment action. With the increasing concern for antimicrobial resistance, it is strongly recommended to treat only the mammary quarters presenting intramammary infection. For this reason, a timely and accurate diagnosis is fundamental. The possibility to detect and characterize mastitis directly on farm would be very useful to choose the correct management protocol. Some on-field diagnostic tools are already routinely applied to detect mastitis, such as the California Mastitis Test and on-farm culture. Other instruments are emerging to perform a timely diagnosis and to characterize mastitis, such as Infra-Red Thermography, mammary ultrasound evaluation and blood gas analysis, even if their application still needs to be improved. The main purpose of this article is to present an overview of the methods currently used to control, detect, and characterize mastitis in dairy cows, in order to perform a timely diagnosis and to choose the most appropriate management protocol, with a specific focus on on-farm diagnostic tools.

show abstract

Multiple-Vessel-Based Blood Gas Profiles Analysis Revealed the Potential of Blood Oxygen in Mammary Vein as Indicator of Mammary Gland Health Risk of High-Yielding Dairy Cows

Cited by 2 publications

References 32 publications

Heat stress affects dairy cow health status through blood oxygen availability

Heat stress affects dairy cow health status through blood oxygen availability

Mastitis in Dairy Cattle: On-Farm Diagnostics and Future Perspectives

Contact Info

Product

Resources

About