Multiple viral hepatitis in injection drug users and associated risk factors

Reimer, Jens; Lorenzen, Juergen; Baetz, Bernhard; Fischer, Benedikt; Rehm, Jüergen; Haasen, Christian; Backmund, Markus

doi:10.1111/j.1440-1746.2006.04358.x

Cited by 47 publications

(42 citation statements)

References 31 publications

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“…5,[9][10][11] Injectors are exposed to life-threatening health risks such as drug overdoses, bloodborne viral infections, endocarditis, and others. [12][13][14] Those who remain untreated or who are outside the social and health care system are known to experience higher rates of morbidity and mortality. [15][16][17] Given that abstinence-oriented therapies for opioid addiction have relatively low efficacy, 18 opioid agonist substitution is currently the most effective treatment option.…”

Section: Introductionmentioning

confidence: 99%

The North American Opiate Medication Initiative (NAOMI): Profile of Participants in North America’s First Trial of Heroin-Assisted Treatment

et al. 2008

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Standardized assessment instruments such as the European Addiction Severity Index and the Maudsley Addiction Profile were employed. A total of 251 individuals were randomized from Vancouver, BC (192, 76.5%), and Montreal, Quebec (59, 23.5%); 38.5% were female, the mean age was 39.7 years (SD:8.6), and participants had injected drugs for 16.5 years (SD:9.9), on average. In the prior month, heroin was used a mean of 26.5 days (SD:7.4) and cocaine 16 days (SD;12.6). Vancouver had significantly more patients residing in unstable housing (88.5 vs. 22%; pG0.001) and higher use of smoked crack cocaine (16.9 days vs. 2.3 days in the prior month; pG0.001), while a significantly higher proportion of Montreal participants reported needle sharing in the prior 6 months (25% vs. 3.7%; pG0.001). In many respects, the patient cohort was similar to the European trials; however, NAOMI had a higher proportion of female participants and participants residing in unstable housing. This study suggests that the NAOMI study successfully recruited participants with a profile indicated for HAT. It also raises concern about the high levels of crack cocaine use and social marginalization.

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Section: Introductionmentioning

confidence: 99%

The North American Opiate Medication Initiative (NAOMI): Profile of Participants in North America’s First Trial of Heroin-Assisted Treatment

et al. 2008

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“…HBV/HCV coinfection is not uncommon and it is mostly found in HBV endemic areas such as Asia, the southern parts of the Sahara, and South America (12,13). On the other hand, in areas with HBV infection prevalence less than 1% (such as Northern Europe), HBV/HCV co-infection is very rare (14, 15); however, this condition mostly common among injection drug users, patients with human immunodeficiency virus, and patients who need hemodialysis or blood transfusion (16).…”

Section: Discussionmentioning

confidence: 99%

The Prevalence of Hepatitis B and C Virus Co-Infection Among a Group of Iranian Population

2017

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Background: The risks of advanced liver disease, cirrhosis, and liver cancer among patients with hepatitis B and C virus co-infection are greater than in patients with either hepatitis B or hepatitis C virus infection. Objectives: The present study sought to assess the prevalence of hepatitis C virus infection among individuals with hepatitis B surface antigen (HBsAg) seropositivity in Mashhad, the largest city in the northeast of Iran. Methods: This cross-sectional descriptive-analytical study was conducted in 2017 on 284 individuals with HBsAg seropositivity who referred from April 2016 to March 2017 to the Central Diagnostic Laboratory of the Academic Center for Education, Culture, and Research, Mashhad, Iran. Commercially available enzyme-linked immunosorbent assay kits were used for detection of hepatitis C virus. Moreover, real-time reverse transcriptase-polymerase chain reaction quantification test was performed for individuals with hepatitis C virus antibody.

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“…Uluslararası önerilere uygun olarak, alkol ve madde bağımlıları ve madde kullanımını bırakmış olan kişilerde, HBV infeksiyonu prevalansının yüksek olması nedeniyle serolojik tarama yapılması önerilmektedir (66). Ayrıca, HBsAg-pozitif madde kullanıcılarında, HIV ve HDV koinfeksiyonu prevalansının yüksek olması ve fülminan hepatit riski nedeniyle bu infeksiyonlara yönelik testlerin de yapılması önerilmektedir (63,66,67).…”

Section: Alkol Ve Madde Bağımlılarında Kronik Hepatit B Yönetimiunclassified

“…Ayrıca, HBsAg-pozitif madde kullanıcılarında, HIV ve HDV koinfeksiyonu prevalansının yüksek olması ve fülminan hepatit riski nedeniyle bu infeksiyonlara yönelik testlerin de yapılması önerilmektedir (63,66,67). Alkol ve madde bağımlıları, hepatit A virusu (HAV) serolojisi açısından, tedavi öncesi psikiyatri uzmanı tarafın-dan, anemi açısından ve anemi yönünden değerlendirilme-lidirler (68)(69)(70).…”

Section: Alkol Ve Madde Bağımlılarında Kronik Hepatit B Yönetimiunclassified

Management of Chronic Hepatitis in Special Hosts and Special Situations: A Consensus Report of the Study Group for Viral Hepatitis of the Turkish Society of Clinical Microbiology and Infectious Diseases

Mıstık¹,

Aydın²,

Aksoy³

et al. 2015

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ÖzetTürk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Derneği Viral Hepatit Çalışma Grubu, özel konaklarda ve özel durumlarda kronik hepatit yönetimine ilişkin bir uzlaşı raporu hazırlamak üzere bir toplantı düzenlemiştir. Raporda konuyla ilgili literatür ve uluslararası kılavuzlar, hepatit B virusu (HBV) için sırasıyla kompanse ve dekompanse sirozlu hastalarda kronik hepatit B (KHB) tedavisi, karaciğer nakli sonrası HBV infeksiyonunun nüks etmesinden korunma ve nüks gelişen hastalarda tedavi, fülminan hepatit B tedavisi, hemodiyaliz hastalarında KHB teda- AbstractStudy Group for Viral Hepatitis of the Turkish Society of Clinical Microbiology and Infectious Diseases convened a meeting to develop a consensus report on management of chronic hepatitis in special hosts and special situations. Relevant literature and international guidelines were reviewed, and recommendations agreed are presented at the end of each section such as therapy of chronic hepatitis B (CHB) in patients with compensated and decompensated cirrhosis, prevention and therapy of recurrent hepatitis B after liver transplantation, management of fulminant

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Multiple viral hepatitis in injection drug users and associated risk factors

Cited by 47 publications

References 31 publications

The North American Opiate Medication Initiative (NAOMI): Profile of Participants in North America’s First Trial of Heroin-Assisted Treatment

The North American Opiate Medication Initiative (NAOMI): Profile of Participants in North America’s First Trial of Heroin-Assisted Treatment

The Prevalence of Hepatitis B and C Virus Co-Infection Among a Group of Iranian Population

Management of Chronic Hepatitis in Special Hosts and Special Situations: A Consensus Report of the Study Group for Viral Hepatitis of the Turkish Society of Clinical Microbiology and Infectious Diseases

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