Multisensory Illusions and the Temporal Binding Window

Stevenson, Ryan A.; Zemtsov, Raquel K; Wallace, Mark T.

doi:10.1068/ic903

Cited by 1 publication

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“…Interactions between visual predictive cues and auditory targets could be constrained by multi-sensory temporal binding windows derived from natural scene statistics or neural circuits subserving multisensory integration (van Wassenhove et al, 2007;Stevenson et al, 2011). In mice, the 2 s delay between visual cue offset and sound onset may have proved too long a gap for the visual stimulus offset to facilitate auditory detection (Siemann et al, 2015).…”

Section: Experiments 2: Mice Exploit Temporal Regularities To Perform An Auditory Streaming Taskmentioning

confidence: 99%

Behavioral Approaches to Study Top-Down Influences on Active Listening

et al. 2021

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The massive network of descending corticofugal projections has been long-recognized by anatomists, but their functional contributions to sound processing and auditory-guided behaviors remain a mystery. Most efforts to characterize the auditory corticofugal system have been inductive; wherein function is inferred from a few studies employing a wide range of methods to manipulate varying limbs of the descending system in a variety of species and preparations. An alternative approach, which we focus on here, is to first establish auditory-guided behaviors that reflect the contribution of top-down influences on auditory perception. To this end, we postulate that auditory corticofugal systems may contribute to active listening behaviors in which the timing of bottom-up sound cues can be predicted from top-down signals arising from cross-modal cues, temporal integration, or self-initiated movements. Here, we describe a behavioral framework for investigating how auditory perceptual performance is enhanced when subjects can anticipate the timing of upcoming target sounds. Our first paradigm, studied both in human subjects and mice, reports species-specific differences in visually cued expectation of sound onset in a signal-in-noise detection task. A second paradigm performed in mice reveals the benefits of temporal regularity as a perceptual grouping cue when detecting repeating target tones in complex background noise. A final behavioral approach demonstrates significant improvements in frequency discrimination threshold and perceptual sensitivity when auditory targets are presented at a predictable temporal interval following motor self-initiation of the trial. Collectively, these three behavioral approaches identify paradigms to study top-down influences on sound perception that are amenable to head-fixed preparations in genetically tractable animals, where it is possible to monitor and manipulate particular nodes of the descending auditory pathway with unparalleled precision.

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Section: Experiments 2: Mice Exploit Temporal Regularities To Perform An Auditory Streaming Taskmentioning

confidence: 99%