2016
DOI: 10.1080/00914037.2016.1180622
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Multistimuli responsive polymeric nanosystems for theranostic applications

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Cited by 27 publications
(9 citation statements)
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“…They could represent a new group of anticancer drugs [12].A dual-responsive amphiphilic random copolymer based on tri (ethylene glycol)-methyl ether methacrylate and [1 -(2-acryloxy)-3,3 -dimethyl-6-nitrospiro-(2H-1-benzopyran-2,2 -indoline)] carrying DOX has proven its effectiveness in the case of cancer therapy [13].Two novel multistimuli-responsive drugs for theranostic application polymers, an (N-isopropyl acrylamide-co-itaconic anhydride) copolymer and a macrobranched terpolymer resulting from its partial esterification with monometoxy poly (ethylene glycol) (PEG), have been obtained. Their hybrids with Fe 3 O 4 nanoparticles have produced nanocomposite carriers [14]. Nanotechnology has lately gained increased attention for its effective diagnosis and treatment of some cancer tumors.…”
mentioning
confidence: 99%
“…They could represent a new group of anticancer drugs [12].A dual-responsive amphiphilic random copolymer based on tri (ethylene glycol)-methyl ether methacrylate and [1 -(2-acryloxy)-3,3 -dimethyl-6-nitrospiro-(2H-1-benzopyran-2,2 -indoline)] carrying DOX has proven its effectiveness in the case of cancer therapy [13].Two novel multistimuli-responsive drugs for theranostic application polymers, an (N-isopropyl acrylamide-co-itaconic anhydride) copolymer and a macrobranched terpolymer resulting from its partial esterification with monometoxy poly (ethylene glycol) (PEG), have been obtained. Their hybrids with Fe 3 O 4 nanoparticles have produced nanocomposite carriers [14]. Nanotechnology has lately gained increased attention for its effective diagnosis and treatment of some cancer tumors.…”
mentioning
confidence: 99%
“…The saturation magnetization (δ s ) of the Fe 3 O 4 NPs and MNHG were determined to be about 86.3 and 52.4 emug −1 , respectively. In comparison with similar systems, the developed MNHG exhibited higher magnetization value that qualified it for targeted drug delivery …”
Section: Resultsmentioning
confidence: 91%
“…These nanosystems can be targeted to the required area through external magnets, and the particles no longer show magnetic interaction after eliminating the external magnetic field. Despite, the most important problem regarding the use of MNPs for drug‐delivery purpose is non‐degradable feature of these NPs that restrict their repeated applications for therapeutic efficacy due to their accumulation …”
Section: Introductionmentioning
confidence: 99%
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