Multisystem Inflammatory Syndrome after COVID-19 Vaccination (MIS-V) Presenting with Retropharyngeal Phlegmon in a 15-year-old Boy in Japan

Koga, Takeshi; Yoshimura, Moe; Kubo, Sakiko; Nagai, Miki; Tabata, Katsuhiko; Teranishi, H; Fujino, Misato; Kawana, Hiroshi; Musha, Ikuma; Akioka, Yuko

doi:10.12691/ajmcr-10-2-4

Cited by 2 publications

(1 citation statement)

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“…11 Additional case reports and series demonstrated similar findings. 12–22 Our case and review of other reported cases strengthens the evidence of association between retropharyngeal inflammation and MIS-C. Absence of an association of retropharyngeal inflammation and MIS-C in the literature might have led to a relatively late diagnosis in some patients such as occurred with our patient.…”

Section: Discussionsupporting

confidence: 81%

Retropharyngeal involvement in multisystem inflammatory syndrome in children: Case report and review of literature

Oliva

Ibrahim

McCormick

et al. 2022

SAGE Open Medical Case Reports

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A diagnosis of multisystem inflammatory syndrome in children should be made in the appropriate context and after ruling out other infectious causes. At the same time, clinicians should be diligent as the initial presentation can be unusual and the clinical picture can evolve over time. We report a case that was initially diagnosed as a retropharyngeal infection that did not improve on appropriate antimicrobial coverage. However, as the clinical picture evolved, the patient was found to have multisystem inflammatory syndrome in children and appropriately responded to immunomodulatory treatment. Pediatric infectious diseases practice has been significantly affected by the COVID-19 virus and multisystem inflammatory syndrome in children; data are still emerging as the pandemic evolves. We report this case and conduct literature review to expand the body of evidence about the association between multisystem inflammatory syndrome in children and retropharyngeal involvement.

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Section: Discussionsupporting

confidence: 81%

Retropharyngeal involvement in multisystem inflammatory syndrome in children: Case report and review of literature

Oliva

Ibrahim

McCormick

et al. 2022

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

show abstract

Multisystem Inflammatory Syndrome (MIS) following SARS-CoV-2 vaccinations; a systematic review

Elsaid,

Nune,

Hesham

et al. 2023

Trop Dis Travel Med Vaccines

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Background Although SARS-CoV-2 vaccines are generally safe, there are growing concerns about their link to a potentially life-threatening multi-system inflammatory syndrome following vaccination (MIS-V). We conducted this systematic review to elucidate the prevalence of MIS, severity, treatment, and outcomes following SARS-CoV-2 vaccination. Methods We searched PubMed, Scopus, ScienceDirect, Google Scholar, Virtual Health Library (VHL), Cochrane Library, and Web of Science databases for articles and case reports about MIS-V. We performed a qualitative analysis of individual cases from the included studies. Results Of the 1366 studies identified by database search, we retrieved twenty-six case reports and two cohort studies. We analyzed the data of 37 individual cases extracted from 27 articles. The average age of the cases included in this review was 18 (1–67) years, with the most being male (M: F 3.1:1). Of the 37 included cases, the cardiovascular system was the most affected system by MIS (36, 97.3%), followed by the gastrointestinal tract (32, 86.5%). Conclusion MIS after SARS-CoV-2 vaccinations can be fatal, but the incidence is low. Prompt recognition of MIS and ruling out the mimickers are critical in the patient’s early recovery.

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Multisystem Inflammatory Syndrome after COVID-19 Vaccination (MIS-V) Presenting with Retropharyngeal Phlegmon in a 15-year-old Boy in Japan

Cited by 2 publications

References 0 publications

Retropharyngeal involvement in multisystem inflammatory syndrome in children: Case report and review of literature

Retropharyngeal involvement in multisystem inflammatory syndrome in children: Case report and review of literature

Multisystem Inflammatory Syndrome (MIS) following SARS-CoV-2 vaccinations; a systematic review

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