Multivariate Silicification‐Assisted Single Enzyme Structure Augmentation for Improved Enzymatic Activity–Stability Trade‐Off
Guansheng Zheng,
Junxian Yang,
Liang Zhou
et al.
Abstract:The ability to finely tune/balance the structure and rigidity of enzymes to realize both high enzymatic activity and long‐term stability is highly desired but highly challenging. In this work, we propose a new concept of silica‐enzyme, referred to as “silicazyme”, where solid inorganic silica was controlled hybridization with fragile enzyme under moderate condition at single‐enzyme level, realizing simultaneous structure augmentation, long‐term stability, and high enzymatic activity preservation. A multivariat… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.