Mumps in a highly vaccinated Marshallese community in Arkansas, USA: an outbreak report

Fields, Virgie; Safi, Haytham; Waters, Catherine; Dillaha, Jennifer A.; Capelle, Lucy; Riklon, Sheldon; Wheeler, J. Gary; Haselow, Dirk

doi:10.1016/s1473-3099(18)30607-8

Cited by 47 publications

(43 citation statements)

References 19 publications

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“…Outbreaks of mumps have very occasionally been seen in teenagers, despite a solid vaccination record. This highlights the need for surveillance of all age groups for disease outbreaks, and could be due to waning of protection induced by vaccines that are otherwise regarded as highly efficacious [37][38][39] .…”

Section: Vaccination Is a Lifetime Investmentmentioning

confidence: 99%

Immunization: vital progress, unfinished agenda

Piot

Larson

O’Brien

et al. 2019

Nature

155

127

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Section: Vaccination Is a Lifetime Investmentmentioning

confidence: 99%

Immunization: vital progress, unfinished agenda

Piot

Larson

O’Brien

et al. 2019

Nature

155

127

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Section: Pre-vaccine Postvaccinementioning

confidence: 99%

“…Although mumps was initially successfully controlled by vaccination in developed countries [31][32][33][34]41], sporadic mumps outbreaks began to occur globally [42][43][44][45][46][47][48][49]. During recent years, outbreaks of MuV infections have occurred in adolescent populations, many of whom had been vaccinated with mumps vaccines previously, in the USA [46,50], Canada [42], Australia [49,51], United Kingdom [34,48], and France [14,47]. Several reasons were raised to explain the unexpected occurrence: waning immunity [52,53]; the efficacy of mumps vaccine, which has varied according to the doses of vaccinations and different virus strain used for production of the mumps vaccine [54][55][56][57]; and how much the level of antibody persisted in body with time after vaccination or natural infection among population [24,43].…”

Section: Pre-vaccine Postvaccinementioning

confidence: 99%

Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine

Chang²,

Chen

2020

IJERPH

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Mumps is an important childhood infectious disease caused by mumps virus (MuV). We reviewed the epidemiology, pathogenesis, and vaccine development of mumps. Previous studies were identified using the key words “mumps” and “epidemiology”, “pathogenesis” or “vaccine” in MEDLINE, PubMed, Embase, Web of Science, and Google Scholar. We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide. The performance of mumps vaccination has become an important issue for controlling mumps infections. Vaccine development and routine vaccination are still effective measures to globally reduce the incidence of mumps infections. During outbreaks, a third of MMR vaccine is recommended for groups of persons determined by public authorities.

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“…In Massachusetts, over 250 cases were reported in 2016 and over 170 in 2017, far exceeding the usual state incidence of <10 cases per year [6]. As seen in other recent outbreaks, most cases were associated with academic institutions [4] and other close-contact settings, including prisons [7] and tightly-knit ethnic and religious communities [8,9]. Mumps was reported to the Massachusetts Department of Public Health (MDPH) by 18 colleges and universities in the state, including Harvard University (Harvard), University of Massachusetts Amherst (UMass), and Boston University (BU)-the 3 institutions with the largest numbers of reported cases.…”

Section: Introductionmentioning

confidence: 99%

Combining genomics and epidemiology to track mumps virus transmission in the United States

et al. 2020

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Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks. We paired epidemiological data from public health investigations with analysis of mumps virus whole genome sequences from 201 infected individuals, focusing on Massachusetts university communities. Our analysis suggests continuous, undetected circulation of mumps locally and nationally, including multiple independent introductions into Massachusetts and into individual communities. Despite the presence of these multiple mumps virus lineages, the genomic data show that one lineage has dominated in the US since at least 2006. Widespread transmission was surprising given high vaccination rates, but we found no genetic evidence that variants arising during this outbreak contributed to vaccine escape. Viral genomic data allowed us to reconstruct mumps transmission links not evident from epidemiological data or standard single-gene

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Mumps in a highly vaccinated Marshallese community in Arkansas, USA: an outbreak report

Cited by 47 publications

References 19 publications

Immunization: vital progress, unfinished agenda

Immunization: vital progress, unfinished agenda

Current Status of Mumps Virus Infection: Epidemiology, Pathogenesis, and Vaccine

Combining genomics and epidemiology to track mumps virus transmission in the United States

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