Mung bean sprout extract suppresses Monosodium Glutamate (MSG) effect on the reproductive hormones (FSH and Estrogen) in female Wistar rats

Abstract

Objectives: The purpose of this study was to analyze the effects of mung bean sprout extracts on Follicle stimulating hormone (FSH) and estrogen hormone in female Wistar rats (Rattus norvegicus) exposed to monosodium glutamate (MSG).Materials and Methods: This true experimental study was conducted by using post-test only control group design in the laboratory for animal experimentation of Faculty of Veterinary Medicine - Airlangga University in which Wistar rats (Rattus norvegicus) aged 2 months weighing 150-200 grams were used in this experiment. The samples comprised of 5 rats distributed in each group, totaling 7 groups. I Control Group (P1) was provided with Aquades for 37 days; II (P2) was provided with Aquades for 7 days + MSG 0.03 mg/g of weight on day 8-37; III (P3) was provided with extract of mung bean sprouts 72mg/200g of weight on day 1-37 + MSG 0,03mg/g of weight; IV (P4) was provided with extract of mung bean sprouts 144mg/200g of weight on day 1-37 + MSG 0.03mg/g of weight; V (P5) was provided with Aquades for 7 days + MSG 0.7 mg/g of weight on day 8-37; VI (P6) was provided with extract of mung bean sprouts 72mg/200g of weight on day 1-37 + MSG 0.7mg/g of weight; VII (P7) was provided with extract of mung bean sprouts 144mg/200g of weight on day 1-37 + MSG 0.7mg/g of weight.Serum samples were taken for Follicle Stimulating Hormone (FSH) and Estrogen with ELISA method. Data analysis to test the differences between groups was done by using one way Anova statistical test.Results: MSG dosage 0,03mg/gBB or 0,7mg/g BB was significant difference in FSH (p = 0,011) and estrogen (p = 0,008).Conclusion: obtained from this research that giving green bean sprout extract influence to the level of FSH and estrogen hormone.

Diet enrichment and the reproductive season of captive Sunda Porcupine (Hystrix javanica F. Cuvier 1823)

“…Bean sprout in proprietary feeds for rodent was found sufficient to stimulate the uterus in rat and mice [43,44]. Fatmaningrum and Ningtyas [45] stated that it might influence the level of FSH and estrogen hormone. Vitamin E and vitamin C contained in bean sprout extract act as antioxidants which suppress the effects of free radicals.…”

“…Likewise, mung bean sprouts able to increase the percentage of morphology and motility of spermatozoa [18]. According to Fatmaningrum and Ningtyas [19] described that the administration of mungbean sprout extract caused an increase in FSH and estrogen hormone levels of white rats (Rattus norvegicus). So, this study aimed to extend our current knowledge of H. javanica reproductive rate with emphasis on environmental enrichment (tomato and bean sprout feeding) and the reproductive season.…”