Muscle involvement in sickle cell disease

Rubio, Miguel A.; Díez, Laura; Álvarez, Nuria; Munteis, Elvira

doi:10.1016/j.medcle.2016.03.008

Cited by 3 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The data, in literature, are limited to only a few reports describing mainly adults presenting severe muscular pain involving lower limbs and shoulders. [1][2][3][4][5][6][7][8][9] Recently, a single case of SCD with mandibular abscess was described. 10 A 17-year-old black African female with SCD (homozygous hemoglobin S disease/α-3,7) manifested muscular/peri-muscular tissue involvement secondary to a vaso-occlusive crisis (VOC) with an unusual presentation of the left malar area.…”

Section: E T T E R T O T H E E D I T O R An Unusual Myositis Presenta...mentioning

confidence: 99%

See 1 more Smart Citation

An unusual myositis presentation in a pediatric patient with sickle cell disease

Ribersani

Testi

Palumbo

et al. 2022

Pediatric Blood & Cancer

View full text Add to dashboard Cite

Section: E T T E R T O T H E E D I T O R An Unusual Myositis Presenta...mentioning

confidence: 99%

“…6,10 Few cases (17 patients, mainly young adults) with myositis/myonecrosis are reported in literature. [6][7][8][9][10] Infectious, autoimmune, and iatrogenic causes have to be excluded. Muscles frequently involved are deltoids and quadriceps.…”

Section: E T T E R T O T H E E D I T O R An Unusual Myositis Presenta...mentioning

confidence: 99%

An unusual myositis presentation in a pediatric patient with sickle cell disease

Ribersani

Testi

Palumbo

et al. 2022

Pediatric Blood & Cancer

View full text Add to dashboard Cite

Myonecrosis in a Sickle Cell-Diseased Patient: A Case Report and Literature Review

Almomen

Tawfeeq

Almuhaisin

et al. 2020

Case Reports in Orthopedics

View full text Add to dashboard Cite

Myonecrosis is a condition that results in muscle tissue necrosis, and it is rarely seen in sickle cell patients and often missed because more common manifestations of sickle cell can overlap like vaso-occlusive crises (VOC), which results in pain in the extremities or spine; also osteomyelitis is commonly seen in sickle cell patients. In this article, we present a case of myonecrosis in a sickle cell-diseased patient who presented with left acute atraumatic left foot pain and MRI with contrast showing characteristic image of muscle infarction supportive therapy initiated, and 2-year follow-up did not reveal any physical disabilities; further study and follow-up are needed to know the nature of the disease and avoid improper management of those patients.

show abstract

Myonecrosis in Sickle Cell Anemia: Case Study

Turaga¹,

Boddu

Kipferl

et al. 2017

Am J Case Rep

View full text Add to dashboard Cite

Patient: Male, 27Final Diagnosis: Myonecrosis of sickle cell anaemiaSymptoms: Pain • redness to feet • swelling footMedication: —Clinical Procedure: MRISpecialty: PodiatryObjective:Rare diseaseBackground:Myonecrosis is one of the more poorly studied, painful manifestations of sickle cell crisis. Medical literature is sparse detailing the manifestations and management of such symptoms. In myonecrosis, red cells containing sickle hemoglobin become rigid, resulting in reduced blood flow and myonecrosis.Case Report:We present a case study of a patient in sickle cell crisis with an episode of acute pain and swelling to the intrinsic muscles of the foot as a prominent feature of the crises. Although muscle biopsy is considered the gold standard for the diagnosis of myositis or myonecrosis, a low intensity signal on T1 and high intensity signal on T2 at the affected muscle belly can be as conclusive as imaging studies. In an actively sickling patient any invasive intervention should be avoided as it can result in ischemic necrosis of the tissues, due to interruption of capillary flow in end-arteries.Conclusions:Early recognition is critical in sickle cell disease management, allowing for prompt and aggressive fluid resuscitation which remains a cornerstone in the management of most sickle cell vaso-occlusive crises. In this instance, off loading the extremity and early fluid resuscitation resolved the pain and swelling and prevented myonecrosis.

show abstract

Muscle involvement in sickle cell disease

Cited by 3 publications

References 8 publications

An unusual myositis presentation in a pediatric patient with sickle cell disease

An unusual myositis presentation in a pediatric patient with sickle cell disease

Myonecrosis in a Sickle Cell-Diseased Patient: A Case Report and Literature Review

Myonecrosis in Sickle Cell Anemia: Case Study

Contact Info

Product

Resources

About