Muscle ultrasound

Hwang, Hsuen-En; Hsu, Ting-Rong; Lee, Yueh-Hui; Wang, Hsin‐Kai; Chiou, Hong‐Jen; Niu, Dau‐Ming

doi:10.1097/md.0000000000008415

Cited by 14 publications

(8 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We found that some texture feature parameters for rectus femoris muscles and sartorius muscles were significantly different between the IOPD and LOPD groups. This result is consistent with the findings of Hwang et al, who used a muscle ultrasound scoring system based on modified Heckmatt’s qualitative criteria to distinguish IOPD from LOPD, achieving 100.0% sensitivity and 84.0% specificity [ 42 ]. They proposed that the echogenicity of muscle tissues in newborns and infants can increase because newborns and infants have small muscle fibers and a relatively high proportion of endomysial and perimysial connective tissues.…”

Section: Discussionsupporting

confidence: 90%

“…Therefore, we suggest that disease severity can be estimated using changes in the texture feature parameters of muscles in patients with IOPD. Although a fluorometric GAA activity assay based on dried blood spots is the predominant method for diagnosing Pompe disease, it does not effectively distinguish between IOPD and LOPD or false-positive cases with pseudodeficiency mutation [ 42 , 43 ]. In future research, texture-feature parametric imaging will be a useful method for differentiating IOPD from LOPD and as a correlate of changes in clinical parameters.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of Quantitative Muscle Ultrasound Using Texture-Feature Parametric Imaging in Detecting Pompe Disease in Children

Chiou

Yeh

Hwang

et al. 2019

Entropy

Self Cite

View full text Add to dashboard Cite

Pompe disease is a hereditary neuromuscular disorder attributed to acid α-glucosidase deficiency, and accurately identifying this disease is essential. Our aim was to discriminate normal muscles from neuropathic muscles in children affected by Pompe disease using a texture-feature parametric imaging method that simultaneously considers microstructure and macrostructure. The study included 22 children aged 0.02–54 months with Pompe disease and six healthy children aged 2–12 months with normal muscles. For each subject, transverse ultrasound images of the bilateral rectus femoris and sartorius muscles were obtained. Gray-level co-occurrence matrix-based Haralick’s features were used for constructing parametric images and identifying neuropathic muscles: autocorrelation (AUT), contrast, energy (ENE), entropy (ENT), maximum probability (MAXP), variance (VAR), and cluster prominence (CPR). Stepwise regression was used in feature selection. The Fisher linear discriminant analysis was used for combination of the selected features to distinguish between normal and pathological muscles. The VAR and CPR were the optimal feature set for classifying normal and pathological rectus femoris muscles, whereas the ENE, VAR, and CPR were the optimal feature set for distinguishing between normal and pathological sartorius muscles. The two feature sets were combined to discriminate between children with and without neuropathic muscles affected by Pompe disease, achieving an accuracy of 94.6%, a specificity of 100%, a sensitivity of 93.2%, and an area under the receiver operating characteristic curve of 0.98 ± 0.02. The CPR for the rectus femoris muscles and the AUT, ENT, MAXP, and VAR for the sartorius muscles exhibited statistically significant differences in distinguishing between the infantile-onset Pompe disease and late-onset Pompe disease groups (p < 0.05). Texture-feature parametric imaging can be used to quantify and map tissue structures in skeletal muscles and distinguish between pathological and normal muscles in children or newborns.

show abstract

Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

Efficacy of Quantitative Muscle Ultrasound Using Texture-Feature Parametric Imaging in Detecting Pompe Disease in Children

Chiou

Yeh

Hwang

et al. 2019

Entropy

Self Cite

View full text Add to dashboard Cite

show abstract

“…The use of qualitative diagnostic ultrasound for muscle disorders has been reported in Duchenne muscular dystrophy [13], Pompe disease [14,27] and other inherited muscular disorders [28]. Recently, Ticinesi et al reviewed the published studies on detecting muscle mass loss in older populations [9].…”

Section: Discussionmentioning

confidence: 99%

“…State-of-the-art quantitative ultrasonography, which calculates the first and higher-order statistics according to the probability density function of grayscale, is widely available. The texture analysis of skeletal muscle ultrasonography has been shown to provide an objective and reliable method for differentiation between healthy and diseased muscles, such as Duchenne muscular dystrophy [13] and Pompe disease [14]. Quantitative texture features would represent the orientation and distribution of the echo patterns in muscular structures.…”

Section: Introductionmentioning

confidence: 99%

The Quantitative Skeletal Muscle Ultrasonography in Elderly with Dynapenia but Not Sarcopenia Using Texture Analysis

et al. 2020

View full text Add to dashboard Cite

(1) Background: Dynapenia is defined as lower muscle strength alone. Only a few studies have investigated muscle quality in subjects with dynapenia. (2) Methods: The muscle quality, characterized by texture parameters of biceps brachii, triceps brachii, rectus femoris, and medial gastrocnemius muscles, were collected using ultrasonography. The risk of dynapenia was assessed by the multiple logistic regression model. (3) Results: There were a total of 36 participants (72.7 ± 5.8 yrs, 1:1 case-control matched). The values of texture parameters of autocorrelation (AUT) and sum variance (SVAR) in all four muscles were higher in the dynapenia group significantly (p < 0.05). AUT and SVAR had the significant associations for dynapenia in biceps (dds ratio[OR]:2.51, 95% CI = 1.25–5.07 for AUT; OR = 1.45, 95% CI:1.1–1.91 for SVAR), triceps (OR: 2.48, 95% CI = 1.60–5.3 for AUT; OR: 1.57, 95% CI = 1.08–2.28 for SVAR), and rectus femoris (OR: 1.58, 95% CI = 1.01–2.46 for AUT; OR: 1.2, 95% CI = 1.0–1.44 for SVAR). The areas under the receiver-operating curves of all texture parameters was between 0.84–0.94 after adjusting confounding factors. (4) Conclusions: The muscle quality in the dynapenia can be detected by the texture-feature quantitative ultrasound. Ultrasound measurement in the aging muscle might be promising, and further studies should validate its application in the context of dynapenia.

show abstract

“…Muscle US has been used to differentiate between affected and unaffected muscle tissue in both IOPD and LOPD infants and can be done in a matter of minutes [ 13 ]. Previous studies have indicated that worsening muscle US findings correlate with increased CK/ALT and diminished physical function in clinically diagnosed adults with LOPD [ 14 , 15 ]. Muscle US is less expensive than MRI, can be provided at point-of-care, and does not require sedation, making it an optimal modality for evaluating muscle.…”

Section: Introductionmentioning

confidence: 99%