Mussel-inspired self-coating at macro-interface with improved biocompatibility and bioactivity via dopamine grafted heparin-like polymers and heparin

Ma, Lang; Qin, Hailong; Cheng, Chong; Xia, Yi; He, Chao; Nie, Chuanxiong; Wang, Lingren; Zhao, Changsheng

doi:10.1039/c3tb21388a

Cited by 173 publications

(135 citation statements)

References 67 publications

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“…The resultant heparin adhesive can form a biocompatible coating on various substrates ( Fig. 13a and b) [172,173]. Ma et al synthesized dopamine-grafted heparin and heparin-like polymer, which were used to form a biocompatible self-coating on PES dialysis membranes.…”

Section: Pre-decoration Of Other Polymersmentioning

confidence: 99%

Surface engineering of polymer membranes via mussel-inspired chemistry

Yang

Luo

et al. 2015

Journal of Membrane Science

381

202

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Section: Pre-decoration Of Other Polymersmentioning

confidence: 99%

Surface engineering of polymer membranes via mussel-inspired chemistry

Yang

Luo

et al. 2015

Journal of Membrane Science

381

202

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Section: Introductionmentioning

confidence: 99%

Grafting of Poly (Cysteine Methacrylate) Brush from Polysulfone Membrane via Surface-Initiated ATRP and Their Anti-Protein Fouling Property

Yang¹

2017

JFBI

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In this paper, we first grafted the poly cysteine methacrylate (pCysMA) brush on polysulfone membrane by surface-initiated atomic-transfer radical polymerization and studied for their antifouling properties. The surface topological structure, chemical composition, and wettability of the as-prepared surface are characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), fourier transform infrared spectra (ATR-FTIR), and water contact angle (WCA) measurements. The hydrophilicity and anti-biofouling activities of the polymer brush surface were evaluated by protein adsorption test. The results displayed that the pCysMA shows better hydrophilicity and effectively resisted the adsorption of bovine serum albumin (BSA) protein.

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“…However, the hydrophobic nature of PSU membranes limited its biomedical applications. Hydrophilic surface modification of the membrane would be an effective approach to solve this problem [5][6][7][8][9]. A lot of surface modification approaches had been conducted to gain anti-fouling surfaces [6].…”

Section: Introductionmentioning

confidence: 99%

Surface modification of polysulfones via one-pot ATRP and click chemistry: Zwitterionic graft complex and their hemocompatibility

Xia

et al. 2016

Fibers Polym

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Zwitterionic sulfobetaine groups were grafted onto polysulfone (PSU) membrane surface with 2-azidoethyl methacrylate and N,N-diethyl-N-propargyl-N-(3-sulfopropyl) ammonium (DEPAS) via surface-initiated Atom Transfer Radical Polymerization (ATRP) and "click" chemistry in a two-step process. The PSU membranes were fully characterized by attenuated total reflectance Fourier transform infrared spectra (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), and static water contact angle (WCA) measurement. Results showed that zwitterionic monomers were efficiently grafted onto PSU surfaces. The water contact angle, bovine serum albumin (BSA) protein adsorption and platelet adhesion were obviously decreased after grafting zwitterionic sulfobetaine groups onto the membrane surface. These indicated that the zwitterionic sulfobetaine modified PSU membranes presented good biocompatibility. This study provides a new approach for surface modification of polysulfone with different functionalities.

show abstract

Mussel-inspired self-coating at macro-interface with improved biocompatibility and bioactivity via dopamine grafted heparin-like polymers and heparin

Cited by 173 publications

References 67 publications

Surface engineering of polymer membranes via mussel-inspired chemistry

Surface engineering of polymer membranes via mussel-inspired chemistry

Grafting of Poly (Cysteine Methacrylate) Brush from Polysulfone Membrane via Surface-Initiated ATRP and Their Anti-Protein Fouling Property

Surface modification of polysulfones via one-pot ATRP and click chemistry: Zwitterionic graft complex and their hemocompatibility

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