RSC Chem. Biol.
 2022
DOI: 10.1039/d2cb00064d
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Mutant polymerases capable of 2′ fluoro-modified nucleic acid synthesis and amplification with improved accuracy

Trevor A. Christensen
1
,
Kristi Y. Lee
2
,
Simone Z. P. Gottlieb
3
et al.

Abstract: Chemically modified DNA (M-DNA) possesses several useful properties such as expanded reactivity and nuclease resistance, which can enhance the utility of DNA as a biotechnological tool. Native DNA polymerases are...

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