Sleep deprivation causes cognitive problems such as difficulty in establishing a cause-effect relationship, decreased problem-solving abilities, loss of concentration and attention. This study aims to determine the effect of sleep deprivation on interval, chord, rhythmic, melodic dictation skills and perception in students with Musical Hearing Reading and Writing (MHRW) activity, which has a high relationship with learning and memory. The experimental research was conducted with 18 students (14 men and 4 women) who volunteered to participate (Age: 22±2.1, Mean Body Mass Index: 24,6 ± 2.3). To determine the levels of effect of sleeplessness in the study group, the present experimental study made use of the pre-test – post-test model. Although the participants' pretest and post-test success levels were not statistically significant in intervals and chords (p> .05), a statistically significant decrease was found in rhythmic dictation and melodic dictation writing success levels (p < .05). These findings clearly show that sleep deprivation which negatively affected musical learning and memory consolidation significantly decreases the achievement levels of students in MHRW.