MWA Versus RFA in HCC: Superior? Equivalent? Will We Ever Know?

Guiu, Boris

doi:10.1007/s00270-020-02635-x

Cited by 4 publications

(1 citation statement)

References 6 publications

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“…The actual necrosis volume is also influenced by several factors: lesion position, proximity to great vessels or other critical structures and generator parameters. [23] Although MWA is an effective and safe alternative to LR [24], its superiority to RFA has not yet been proven [15], perhaps a study comparing necrosis volumetric assessment in both procedures could help decide which one could show lower LTP.Study limitations Retrospective, monocentric study based on a small group of patients, limited to the evaluation of patients with a single BCLC 0 or A liver lesion treated with radiofrequency ablation and inconsistent imaging follow-up. A prospective trial with longer time interval for follow-up is needed to determine recurrence free-survival and LTP.…”

Section: Discussionmentioning

confidence: 99%

Radiofrequency Ablation in Hepatocellular Carcinoma: Necrosis Volumetric Assessment as a Predictor for Local Tumour Progression, a Retrospective Study

Dumitru,

Grasu,

Iuhas

et al. 2023

Preprint

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(1) Background: Evaluating if necrosis volumetric assessment of pre-/post-RFA in HCC can be an accurate predictor of LTP (local tumor progression) and survival.; (2) Methods: Retrospective, descriptive and analytical study conducted between 01.01.2018 - 30.09.2021 in the Radiology and Medical Imaging Department of Fundeni Clinical Institute. 35 patients, each with one LI-RADS 4 or 5 treated lesion were eligible to be included. Volumetry was performed using OsiriX MD. Initial lesion volume, ideal necrosis volume (0,5-1 cm safety margin) and actual necrosis volume at 1 and 6 months post-procedure were performed; (3) Results: Results and discussions: Actual necrosis volume is influenced by several factors: lesion position, proximity to great vessels or other critical structures. The overall recurrence-free survival rate was similar to data in other studies (77% in the first year post-RFA). This study showed that having the actual necrosis volume at 1 month smaller than ideal necrosis volume is a good predictor for local tumor progression (p &lt; 0,05); (4) Conclusions: Volumetric assessment of necrosis is easily attainable and can help improve prediction of local tumour progression.

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Section: Discussionmentioning

confidence: 99%