Mycobacterial Disease in Renal Allograft Recipients

Abstract

Solid organ transplant recipients have impaired cell-mediated immunity, and are at increased risk of mycobacterial infection. Mycobacterium tuberculosis infection (TB) has a high mortality rate among this population. The diagnosis of tuberculosis in solid organ transplant recipients is a big challenge and needs rapid and accurate modalities. These patients have 3.8 time greater risk of developing extra-pulmonary TB than general population. High index of suspicion and applying with invasive diagnostic procedure are needed for diagnosis of TB in renal transplanted patients.Please cite this paper as: Ardalan MR. Mycobacterial disease in renal allograft recipients. J Renal Inj Prev 2013; 2(2): 83-84.

Quantitative Polymerase Chain Reaction in Diagnosis of Pneumocystis Pneumonia

“…The incidence of PCP in human immunodeficiency virus (HIV)-infected patients has decreased since the introduction of chemoprophylaxis and antiretroviral therapy (4)(5)(6). In fact, various opportunistic infections consisting of PCP, fungi and viruses may involve immunocompromised and transplanted patients (7)(8)(9)(10). Meanwhile, the incidence of PCP in non-HIV immunocompromised patients is increasing (2)(3)(4)(5)(6).…”