2017
DOI: 10.1002/dc.23763
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Myeloid sarcoma identified on liquid‐based cervical cytology samples: A report of two cases

Abstract: The purpose of the Papanicolaou (Pap) smear is to detect primary squamous lesions of the uterine cervix. Although most successful at detection of squamous lesions, the Pap may also detect metastatic carcinomas, sarcomas, and melanomas. We report two rare cases of myeloid sarcoma (MS) of the uterine cervix identified on screening Pap smears with concurrent confirmatory cervical biopsies. The purpose of our study is to identify and report cytologic features of MS on Pap smears utilizing a liquid-based ThinPrep m… Show more

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Cited by 2 publications
(3 citation statements)
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“…[2][3][4][5][6][7][8][9][10][11] Other symptoms include abdominal pain, nausea, diarrhea and hydronephrosis associated with uterine enlargement or mass formation. [12][13][14][15][16][17][18][19][20][21] In the current case, the leukemia relapse at first occurred solely in the uterus without bone marrow involvement; however, bone marrow relapse later occurred. To our knowledge, only two cases of this phenomenon have been previously reported.…”
mentioning
confidence: 51%
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“…[2][3][4][5][6][7][8][9][10][11] Other symptoms include abdominal pain, nausea, diarrhea and hydronephrosis associated with uterine enlargement or mass formation. [12][13][14][15][16][17][18][19][20][21] In the current case, the leukemia relapse at first occurred solely in the uterus without bone marrow involvement; however, bone marrow relapse later occurred. To our knowledge, only two cases of this phenomenon have been previously reported.…”
mentioning
confidence: 51%
“…In almost half of such cases, patients present with abnormal uterine bleeding . Other symptoms include abdominal pain, nausea, diarrhea and hydronephrosis associated with uterine enlargement or mass formation . In the current case, the leukemia relapse at first occurred solely in the uterus without bone marrow involvement; however, bone marrow relapse later occurred.…”
mentioning
confidence: 63%
“…MS is a highly aggressive disease and shows a poor complete response rate after standard chemotherapy [14]; however, the grim survival of this disease can be decelerated to some extent with timely initiation of appropriate therapy that is contingent upon a prompt, accurate, and complete diagnosis. The morphologic features of MS in cytologic preparations such as FNA smears, touch preparations (TPs), and ThinPrep have been reported only sporadically in the literature, and the majority of the published data come from single case reports or small case series [15][16][17][18][19][20][21]. Failure to recognize MS in cytologic specimens combined with the aforementioned complexities associated with this diagnosis may delay or even misdiagnose this dismal disease.…”
Section: Introductionmentioning
confidence: 99%