Myocardial Performance Index as a Predictor of IN-Hospital and Short Term Outcome after First Acute Myocardial Infarction

Abstract

Introduction: Acute myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. It affects both systolic and diastolic functions. The Doppler index of combined systolic and diastolic function (Tei index) was found to be able to separate patients with normal ventricular function from patients with ventricular dysfunction. (Tei) index has been reported to correlate better with patients outcome than conventional echocardiographic parameters in different myocardial diseases. Objectives:The aim of this study is to assess the value of the left ventricular myocardial performance index (MPI) in the prediction of in hospital and short term outcome after first acute myocardial infarction. Material and Methods:Sixty patients admitted to the coronary care unit with first attack of acute myocardial infarction and sixty healthy age and sex comparable group were included. Doppler waves from inverted simultaneous display of the mitral inflow and left ventricular outflow was recorded. Isovolumetric contraction time (IVCT), isovolumetric relaxation time (IVRT) and ejection Time (ET) were measured and then MPI was calculated using the formula (MPI2=IVCT+IVRT/ET).Results: Doppler derived MPI was significantly higher in myocardial infarction patients complicated by heart failure, arrhythmias, post myocardial infarction angina and cardiac death. MPI was inversely correlated with Ejection fraction and positively correlated with EDD and ESD. Conclusion:Myocardial performance index predicts in-hospital and short term outcomes after first acute myocardial infarction.