Myocardial Performance Index Derived from Preejection Period: A Novel and Feasible Parameter in Evaluation of Cardiac Performance in Patients with Permanent Atrial Fibrillation

Su, Ho‐Ming; Lin, Tsung-Hsien; Hsu, Po-Chao; Chu, Chun-Yuan; Lee, Wen-Hsien; Lee, Chee-Siong; Lai, Wen‐Ter; Sheu, Sheng‐Hsiung; Voon, Wen‐Chol

doi:10.1111/j.1540-8175.2011.01491.x

Cited by 7 publications

(8 citation statements)

References 23 publications

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“…Therefore, we concluded that a higher Em is associated with a better diastolic function. Su et al recently reported that Ea and E/Em were reported to be significantly correlated with time constant of isovolumic LV pressure decline and LV filling pressure in atrial fibrillation patients [14]. In this study, IVRT had a moderately strong correlation with Em and a moderate correlation with E/Em.…”

Section: Discussionsupporting

confidence: 55%

Myocardial Performance Index in Neurocardiogenic Syncope Patients

et al. 2014

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BackgroundMany syncopes resulting from neural reflexes in various conditions are called neurocardiogenic syncope (NCS). We aimed to investigate the presence of left ventricular (LV) myocardial performance index (MPI) in patients with NCS, which was diagnosed with head-up tilt table test (HUTT), and the accurateness of the test in order to use it as a method in patients with NCS. Assuming the MPI as a potential cause of syncope, we assessed the Tei index with non-invasive tissue Doppler echocardiography method.MethodsConsecutive outpatients with a history of recurrent unexplained syncope underwent HUTT. Twenty-nine HUTT (+) patients (24 female and five male, mean age: 30 ± 15 years) as the study group and HUTT (-) 23 healthy patients (six female and 17 male, mean age: 34 ± 16 years) as the control group were included into the study. Conventional and tissue Doppler echocardiography was performed to both groups. The MPI was determined by using PW Doppler. Measurements of Doppler time intervals, according to Tei index ((isovolumic contraction time + isovolumic relaxation time)/ejection time) is calculated as (a - b/b), where “a” is the interval between cessation and onset of the mitral inflow, and “b” is the ejection time (ET) at the LV outflow.ResultsWhen comparing the groups in terms of MPI and ET, there was significant difference between groups. Patients with NCS had significantly longer ET and lower MPI value than control group (284 ± 24 ms vs. 260 ± 24 ms, P < 0.001, respectively and 0.44 ± 0.7 vs. 0.52 ± 0.8, P < 0.001, respectively). There was no significant difference in ejection fraction between groups.ConclusionIn the present study, LV MPI value decreases in patients with NCS.

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Section: Discussionsupporting

confidence: 55%

Myocardial Performance Index in Neurocardiogenic Syncope Patients

et al. 2014

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“…In the present study, we also demonstrated that using the index beat to measure PEPa-derived MPI was as accurate as and less timeconsuming than the onerous method of averaging of multiple cardiac cycles. In addition, our recent study showed that the PEPa-derived MPI measured from average method was significantly associated with left ventricular systolic and diastolic function [17]. The present study demonstrated that PEPa-derived MPI measured by index beat method also had a significant correlation with LVEF and Ea.…”

Section: Discussionmentioning

confidence: 59%

“…Therefore, using tissue Doppler echocardiography, we can measure PEPa, defined as the interval measured from the onset of QRS to the onset of the systolic mitral annular velocity pattern, ETa, defined as the interval measured from the onset to the end of systolic mitral annular velocity pattern, and IVRTa, defined as the interval measured from the end of systolic mitral annular velocity pattern to the onset of diastolic mitral annular velocity pattern on the same cardiac cycle. Recently, we have demonstrated that the PEPa-derived MPI, defined as the ratio of PEPa + IVRTa to ETa, was significantly associated with echocardiographic left ventricular systolic and diastolic function in AF patients [17]. Because the PEPa-derived MPI can concurrently reflect left ventricular systolic and diastolic function, it has a potential to become a useful parameter in prediction of adverse CV events in AF patients.…”

Section: Introductionmentioning

confidence: 98%

Myocardial performance index derived from pre-ejection period as a novel and useful predictor of cardiovascular events in atrial fibrillation

Chu

Lee

Hsu

et al. 2015

Journal of Cardiology

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“…The MPI, the Tei index, also called the MPI-Tei index, was defined as the ratio of IVCT along with IVRT to ET1, whereas the PEP-derived MPI was defined as the ratio of PEP along with IVRT to ET. 8 …”

Section: Methodsmentioning

confidence: 99%

“…Preejection period (PEP) can easily be obtained in AF patients, and PEP may be used instead of IVCT in AF patients. 8 PEP interval was measured from the onset of QRS to the onset of the systolic mitral annular velocity pattern. Su et al 9 defined the “PEPa-derived MPI” in patients with AF; it is calculated as the ratio of PEPa along with IVRTa to ETa.…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Tei Index and PEP-Derived Myocardial Performance Index in Sinus Rhythm

et al. 2015

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The goal of this study was to evaluate the preejection time (PEP)-derived myocardial performance index (MPI) in hypertensive (HT) patients with sinus rhythm and its relationship to the classic Tei index.One hundred five patients were enrolled in the study (65 HT and 40 control subjects). The mean age of all patients was 50.5 ± 15 years and 60% were female. Echocardiography was performed on all patients. MPI was measured with the classic Tei method (MPI-Tei index) and the PEP-derived MPI method by using tissue Doppler echocardiography. Although the MPI-Tei index is defined as the ratio of isovolumetric contraction time (IVCT) along with isovolumetric relaxation time (IVRT) to ejection time (ET), PEP-derived MPI is defined as the ratio of PEP and IVRT to ET. We compared echocardiographic data between the HT group and the control group.MPI-Tei index and the PEP-derived MPI values were higher in the HT group compared with controls (0.52 ± 0.10 vs 0.39 ± 0.07, P < 0.001, and 0.51 ± 0.09 vs 0.39 ± 0.07). PEP-derived MPI was strongly correlated with the MPI-Tei index (r = 0.945, P < 0.001).Our study determined that the PEP-derived MPI might be used in the evaluation of left ventricular function in patients with HT, similar to the classic MPI-Tei index.

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Myocardial Performance Index Derived from Preejection Period: A Novel and Feasible Parameter in Evaluation of Cardiac Performance in Patients with Permanent Atrial Fibrillation

Abstract: PEPa-derived MPI had a significant correlation with echocardiographic left ventricular diastolic and systolic function. It may be a novel and feasible indicator in assessment of global left ventricular function in patients with permanent atrial fibrillation.

Cited by 7 publications

References 23 publications

Myocardial Performance Index in Neurocardiogenic Syncope Patients

Myocardial Performance Index in Neurocardiogenic Syncope Patients

Myocardial performance index derived from pre-ejection period as a novel and useful predictor of cardiovascular events in atrial fibrillation

Relationship Between Tei Index and PEP-Derived Myocardial Performance Index in Sinus Rhythm

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